ReviewImmunologic research2010
Class I MHC molecules as probes of membrane patchiness: from biophysical measurements to modulation of immune responses.
Review in Immunologic research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Strategies to overcome low MHC-I expression in paediatric and adult tumours.Immunotherapy advances · 2024Review
- Factors contributing to the potency of CD8Trends in immunology · 2023Review
- Open MHC Class I Conformers: A Look through the Looking Glass.International journal of molecular sciences · 2021Review
- Mapping the stochastic sequence of individual ligand-receptor binding events to cellular activation: T cells act on the rare events.Science signaling · 2019Article
- Visualizing glycans on single cells and tissues-Visualizing glycans on single cells and tissues.Current opinion in chemical biology · 2017Review
- Tracking surface glycans on live cancer cells with single-molecule sensitivity.Angewandte Chemie (International ed. in English) · 2015Article
- Quantitative study of the elastic modulus of loosely attached cells in AFM indentation experiments.Biophysical journal · 2013Article
- Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.PloS one · 2012Article
- Membrane raft organization is more sensitive to disruption by (n-3) PUFA than nonraft organization in EL4 and B cells.The Journal of nutrition · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Here I summarize decades of work using the biophysics of class I MHC molecules to probe the patchiness and heterogeneity of cell surfaces. This program began as a study of membranes generally. MHC molecules were a convenient probe. However, in recent years, it has become clear that the lateral distribution, clustering, of class I MHC molecules in the membrane affects their recognition by effector CTL. This offers the possibility of enhancing or reducing T-cell recognition of targets by altering the clustering of their membrane proteins.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.