Evidence map›Paper›PMID 20077024›Full record

ReviewMolecules and cells2010

Autophagy in viral replication and pathogenesis.

Donna Sir, Jing-hsiung James Ou

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecules and cells, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 100 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Gadd45 Proteins in Immunity 2.0.Advances in experimental medicine and biology · 2022
    Article
  8. Autophagy receptors as viral targets.Cellular & molecular biology letters · 2021
    Review
  9. Review
  10. Functions of ROS in Macrophages and Antimicrobial Immunity.Antioxidants (Basel, Switzerland) · 2021
    Review
  11. Autophagy in liver diseases.World journal of hepatology · 2021
    Review
  12. Studies Progression on the Function of Autophagy in Viral Infection.Frontiers in cell and developmental biology · 2021
    Review
  13. Article
  14. Activation of mTOR Signaling Pathway in Hepatocellular Carcinoma.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donna SirDepartment of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA.
Jing-hsiung James Ou
University of Southern California · US

Funding

Virus-host interactions in hepatocarcinogenesisP01CA123328 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OU, J.-H. JAMES · 2007 to 2011
$5.3M
NCI NIH HHS P01 CA123328
6 · The paper itself

Abstract

Autophagy is a catabolic process that is important for the removal of damaged organelles and long-lived proteins for the maintenance of cellular homeostasis. It can also serve as innate immunity to remove intracellular microbial pathogens. A growing list of viruses has been shown to affect this cellular pathway. Some viruses suppress this pathway for their survival, while others enhance or exploit this pathway to benefit their replication. The effect of viruses on autophagy may also sensitize cells to death or enhance cell survival and play a critical role in viral pathogenesis. In this article, we review the relationships between different viruses and autophagy and discuss how these relationships may affect viruses and their host cells.

Indexed as

AutophagyVirus ReplicationAnimalsCell SurvivalHost-Pathogen InteractionsHumansImmunity, InnateMembrane FusionVirus Diseases

Identifiers

PMID20077024
PMCPMC3115743
OpenAlexW2017670435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.