Evidence map›Paper›PMID 20077004›Full record

ArticleVeterinary research communications2010

Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving.

Yoshio Kiku, Tomomi Ozawa, Shiro Kushibiki, Madoka Sudo, Kouhei Kitazaki, Noriaki Abe, Takahashi Hideyuki, Tomohito Hayashi

Abstract read
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In one paragraph

Article in Veterinary research communications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yoshio KikuNational Institute of Animal Health, 3-1-5 Kan-nondai, Tsukuba Ibaraki, 305-0856, Japan.
Tomomi Ozawa
Shiro Kushibiki
Madoka Sudo
Kouhei Kitazaki
Noriaki Abe
Takahashi Hideyuki
Tomohito Hayashi
National Institute of Animal Health · JPInstitute of Livestock and Grassland Science · JPFukuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the postpartum period there is a high incidence of mastitis in dairy cows. The reason for this increased risk of mastitis still remains unclear. Since leukocytes in colostrum have an important role in preventing the onset of mastitis, we investigated the leukocyte populations, which express CD4, CD8, CD14, CD21 or WC1, in colostrum as well as in blood obtained from 14 Holstein cows. Eight cows developed mastitis within a week after calving and the other 6 remained healthy. The percentage of CD14+ cells in colostrum was significantly lower in mastitic cows than in healthy cows. There were no significant differences in other marker positive cells either in the colostrum or in the blood. The CD14+ cells in colostrum play an important role of defense against invading microorganisms in the mammary glands. Our results suggested that the lower percentage of CD14+ cells in colostrum might predict the incidence of mastitis in the following period.

Indexed as

3-Hydroxybutyric AcidAnimalsAspartate AminotransferasesBlood ProteinsBlood Urea NitrogenCattleCholesterolColostrumFatty Acids, NonesterifiedFemaleKetone BodiesLeukocyte CountLeukocytes, MononuclearLipopolysaccharide ReceptorsMastitis, BovineMilk3-Hydroxybutyric AcidAspartate AminotransferasesBlood ProteinsCholesterolFatty Acids, NonesterifiedKetone BodiesLipopolysaccharide Receptors

Identifiers

PMID20077004
OpenAlexW2038267924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.