Evidence map›Paper›PMID 20076976›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2010

Evolving classification systems for cancer cachexia: ready for clinical practice?

David Blum, Aurelius Omlin, Ken Fearon, Vickie Baracos, Lukas Radbruch, Stein Kaasa, Florian Strasser, European Palliative Care Research Collaborative

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03245658 (The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03245658 phase2withdrawnnot on this mapstarted 2017, after this paper: background citation

The Effect of Medical Cannabis Inpatients With Palliative Pancreatic Cancer

TypeinterventionalSponsorJens Rikardt AndersenRan2017 to 2018Enrolled0ConditionsNeoplasms Pancreatic, Cachexia, Cancer, CannabisArmsTHC and CBD Mixture
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Metabolomics and its Applications in Cancer Cachexia.Frontiers in molecular biosciences · 2022
    Review
  8. Article
  9. A retrospective cohort study to investigate the incidence of cancer-related weight loss during chemotherapy in gastric cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  10. Article
  11. Incidence and frequency of cancer cachexia during chemotherapy for advanced pancreatic ductal adenocarcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  12. Displaced Myonuclei in Cancer Cachexia Suggest Altered Innervation.International journal of molecular sciences · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The assessment of anorexia in patients with cancer: cut-off values for the FAACT-A/CS and the VAS for appetite.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  18. Cachexia in cancer: what is in the definition?BMJ open gastroenterology · 2016
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David BlumOncological Palliative Medicine, Division of Oncology/Hematology, Department of Internal Medicine and Palliative Care Center, Cantonal Hospital, Switzerland.
Aurelius Omlin
Ken Fearon
Vickie Baracos
Lukas Radbruch
Stein Kaasa
Florian Strasser
European Palliative Care Research Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInvoluntary weight loss, the defining factor of cachexia, is a common consequence of advanced cancer. DISCUSSION: This review summarizes the actual cachexia definitions and classification systems (NCCTG-studies, Loprinzi et al.; PG-SGA, Ottery et al.; Cachexia Consensus Conference, Evans et al; Cancer Cachexia Study Group, Fearon et al.; and SCRINIO Working group, Bozzetti et al.).We describe the ongoing development of a new classification system for cancer cachexia, which is based on literature reviews and Delphi processes within the European Palliative Care Research Collaborative. The review describes the evolving understanding of the pathophysiological mechanisms of cachexia and outlines an overview on treatment options.

conclusionIn this review an outlook on the requirements of a new decision guiding instrument is given and the challenges in clinical decision making in palliative are discussed.

Indexed as

Adrenal Cortex HormonesCachexiaCannabinoidsCounselingCyclooxygenase InhibitorsEicosapentaenoic AcidHumansNeoplasmsParenteral Nutrition, TotalProgestinsAdrenal Cortex HormonesCannabinoidsCyclooxygenase InhibitorsEicosapentaenoic AcidProgestins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.