Evidence map›Paper›PMID 20075926›Full record

ReviewNature reviews. Microbiology2010

Bacterial manipulation of innate immunity to promote infection.

Lautaro Diacovich, Jean-Pierre Gorvel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 304 citations in OpenAlex.

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  7. International journal of molecular sciences · 2026
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  13. Enigmatic roles ofJournal of bacteriology · 2025
    Review
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  20. Discovery and Characterization of theInternational journal of molecular sciences · 2024
    Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lautaro DiacovichCentre d'Immunologie de Marseille-Luminy, 1 Aix Marseille Université, Institut National de la Santé et de la Recherche Médicale, U631 and Centre National de la Recherche Scientifique, UMR6102, Marseille, F-13,288, France.
Jean-Pierre Gorvel
Centre d’Immunologie de Marseille-Luminy · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian innate immune response provides a barrier against invading pathogens. Innate immune mechanisms are used by the host to respond to a range of bacterial pathogens in an acute and conserved fashion. Host cells express pattern recognition receptors that sense pathogen-associated molecular patterns. After detection, an arsenal of antimicrobial mechanisms is deployed to kill bacteria in infected cells. Innate immunity also stimulates antigen-specific responses mediated by the adaptive immune system. In response, pathogens manipulate host defence mechanisms to survive and eventually replicate. This Review focuses on the control of host innate immune responses by pathogenic intracellular bacteria.

Indexed as

Immunity, InnateAnimalsAntigens, BacterialBacteriaBacterial InfectionsHost-Pathogen InteractionsHumansImmunity, ActiveVirulenceAntigens, Bacterial

Identifiers

PMID20075926
OpenAlexW2086506975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.