Evidence map›Paper›PMID 20075768›Full record

Trial reportSpine2010

Degenerative spondylolisthesis versus spinal stenosis: does a slip matter? Comparison of baseline characteristics and outcomes (SPORT).

Adam Pearson, Emily Blood, Jon Lurie, Tor Tosteson, William A Abdu, Alan Hillibrand, Keith Bridwell, James Weinstein

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Spine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Surgery for adult spondylolisthesis: a systematic review of the evidence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016
    Pooled it
  3. Management of lumbar spinal stenosis.BMJ (Clinical research ed.) · 2016
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Specific foraminal changes originate from degenerative spondylolisthesis on computed tomographic images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Central lumbar spinal stenosis: natural history of non-surgical patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Article
  17. The outcome of decompression alone for lumbar spinal stenosis with degenerative spondylolisthesis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2017
    Article
  18. Article
  19. Disc degeneration-related clinical phenotypes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014
    Review
  20. Mechanical low back pain--a rheumatologist's view.Nature reviews. Rheumatology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adam PearsonDepartment of Orthopaedics, Dartmouth Medical School, Lebanon, NH 03756, USA. adam.m.pearson@hitchcock.org
Emily Blood
Jon Lurie
Tor Tosteson
William A Abdu
Alan Hillibrand
Keith Bridwell
James Weinstein
Pearson (United States) · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIALU01AR045444 · NIAMS · DARTMOUTH COLLEGE · PI WEINSTEIN, JAMES N · 1999 to 2013
$20.8M
Prognostic Value of Lumbar Spine MRIP60AR048094 · NIAMS · DARTMOUTH COLLEGE · PI ATLAS, STEVEN J · 2003 to 2007
$6.2M
The Dartmouth Orthopaedics Clinician/Researcher Training Program (DOC/RTP)T32AR049710 · NIAMS · DARTMOUTH-HITCHCOCK CLINIC · PI LURIE, JON D · 2003 to 2018
$2.4M
NCI NIH HHS P30 CA023108NIAMS NIH HHS P60 AR048094NIAMS NIH HHS T32 AR049710NIAMS NIH HHS U01 AR045444
6 · The paper itself

Abstract

STUDY

designAs-treated analysis of the Spine Patient Outcomes Research Trial.

objectiveTo compare baseline characteristics and surgical and nonoperative outcomes between degenerative spondylolisthesis (DS) and spinal stenosis (SPS) patients. SUMMARY OF BACKGROUND DATA: DS and SPS patients are often combined in clinical studies despite differences in underlying pathology and treatment.

methodsThe DS cohort included 601 patients (369 [61%] underwent surgery), and the SPS cohort included 634 patients (394 [62%] underwent surgery). Baseline characteristics were compared between the 2 groups. Changes from baseline for surgical and nonoperative outcomes were compared at 1 and 2 years using longitudinal regression models. Primary outcome measures included the SF-36 bodily pain and physical function scores and the Oswestry Disability Index.

resultsThe DS patients included more females (69% vs. 39%, P < 0.001), were older (66.1 year vs. 64.6 years, P = 0.021), and were less likely to have multilevel stenosis (35% vs. 61%, P < 0.001) compared with the SPS patients. There were no significant baseline differences on any of the main outcome measures. DS patients undergoing surgery were much more likely to be fused than SPS patients (94% vs. 11%, P < 0.001) and improved more with surgery than SPS patients on all primary outcome measures (DS vs. SPS): physical function (+30.4 vs. +25.3, P = 0.004 at 1 year; + 28.3 vs. +21.4, P < 0.001 at 2 years), bodily pain (+32.3 vs. +27.5, P = 0.006 at 1 year; +31.1 vs. +26.1, P = 0.003 at 2 years), and Oswestry Disability Index (-25.9 vs. -21.0, P < 0.001 at 1 year; -24.7 vs. -20.2, P < 0.001 at 2 years). Patients treated nonoperatively improved less than those treated surgically, and there were no significant differences in nonoperative outcomes between the 2 cohorts.

conclusionOverall, DS and SPS patients had similar baseline characteristics. However, DS patients improved more with surgery than SPS patients. Future studies should probably not combine these heterogeneous patient populations.

Indexed as

AdultAgedAged, 80 and overCohort StudiesFemaleHumansLumbar VertebraeMaleMiddle AgedSacrumSpinal StenosisSpondylolisthesisTreatment OutcomeYoung Adult

Identifiers

PMID20075768
PMCPMC2887281
OpenAlexW1991637493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.