ArticleJournal of virology2010
Sustainability of virulence in a phage-bacterial ecosystem.
Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Spatially structured models of viral dynamics: a scoping review.Microbiology and molecular biology reviews : MMBR · 2025Article
- Single-colony resolution of CRISPR-Cas adaptation in E. coli reveals altered spacer-source bias during solid-phase growth.Nucleic acids research · 2025Article
- Multiscale selection in spatially structured populations.Proceedings. Biological sciences · 2024Article
- Virophage infection mode determines ecological and evolutionary changes in a host-virus-virophage system.The ISME journal · 2024Article
- Interspecies ecological competition rejuvenates decayed Geobacter electroactive biofilm.The ISME journal · 2024Article
- Evolution of exploitation and replication of giant viruses and virophages.Virus evolution · 2024Article
- Bacteriophage therapy for drug-resistantFrontiers in cellular and infection microbiology · 2024Review
- Article
- Mechanisms regulating the CRISPR-Cas systems.Frontiers in microbiology · 2023Review
- Eco-evolutionary feedbacks mediated by bacterial membrane vesicles.FEMS microbiology reviews · 2021Review
- Article
- Environmental pH is a key modulator of Staphylococcus aureus biofilm development under predation by the virulent phage phiIPLA-RODI.The ISME journal · 2021Article
- Bacteriophages presence in nature and their role in the natural selection of bacterial populations.Acta bio-medica : Atenei Parmensis · 2020Review
- Hitchhiking, collapse, and contingency in phage infections of migrating bacterial populations.The ISME journal · 2020Article
- Bacterial alginate regulators and phage homologs repress CRISPR-Cas immunity.Nature microbiology · 2020Article
- Formation of phage lysis patterns and implications on co-propagation of phages and motile host bacteria.PLoS computational biology · 2020Article
- Engineered bacteriophages as programmable biocontrol agents.Current opinion in biotechnology · 2020Review
- How adaptive immunity constrains the composition and fate of large bacterial populations.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Phage mobility is a core determinant of phage-bacteria coexistence in biofilms.The ISME journal · 2018Article
- Phage-Bacterial Dynamics with Spatial Structure: Self Organization around Phage Sinks Can Promote Increased Cell Densities.Antibiotics (Basel, Switzerland) · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Virulent phages and their bacterial hosts represent an unusual sort of predator-prey system where each time a prey is eaten, hundreds of new predators are born. It is puzzling how, despite the apparent effectiveness of the phage predators, they manage to avoid driving their bacterial prey to extinction. Here we consider a phage-bacterial ecosystem on a two-dimensional (2-d) surface and show that homogeneous space in itself enhances coexistence. We analyze different behavioral mechanisms that can facilitate coexistence in a spatial environment. For example, we find that when the latent times of the phage are allowed to evolve, selection favors "mediocre killers," since voracious phage rapidly deplete local resources and go extinct. Our model system thus emphasizes the differences between short-term proliferation and long-term ecosystem sustainability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.