ArticleVeterinary parasitology2010
Limited genetic diversity among Sarcocystis neurona strains infecting southern sea otters precludes distinction between marine and terrestrial isolates.
Article in Veterinary parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 56 citations in OpenAlex.
- Parasite genotype is a risk factor forInternational journal for parasitology. Parasites and wildlife · 2026Article
- Article
- Morphological and Molecular Description of Sarcocystis myodes n. sp. from the Bank Vole (Clethrionomys glareolus) in LithuaniaBiology · 2022Article
- Molecular characterization ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Molecular identification of Sarcocystis wobeseri-like parasites in a new intermediate host species, the white-tailed sea eagle (Haliaeetus albicilla).Parasitology research · 2021Article
- Sarcocystis neurona Transmission from Opossums to Marine Mammals in the Pacific Northwest.EcoHealth · 2021Article
- Seroprevalence of Sarcocystis falcatula in Two Islands of Malaysia using Recombinant Surface Antigen 4.The Korean journal of parasitology · 2020Article
- Reactivity of Horse Sera to Antigens Derived FromFrontiers in veterinary science · 2020Article
- First isolation of Sarcocystis caninum sarcocysts from two domestic dogs (Canis familiaris) from China.Parasitology research · 2018Article
- Morphological and genetic characterisation of Sarcocystis halieti from the great cormorant (Phalacrocorax carbo).Parasitology research · 2018Article
- Identification and genetic characterization of Sarcocystis arctica and Sarcocystis lutrae in red foxes (Vulpes vulpes) from Baltic States and Spain.Parasites & vectors · 2018Article
- Detection and characterization of diverse coccidian protozoa shed by California sea lions.International journal for parasitology. Parasites and wildlife · 2016Article
- A novel Sarcocystis neurona genotype XIII is associated with severe encephalitis in an unexpectedly broad range of marine mammals from the northeastern Pacific Ocean.International journal for parasitology · 2015Article
- An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM).Veterinary parasitology · 2015Review
- Molecular characterization of Sarcocystis species from Polish roe deer based on ssu rRNA and cox1 sequence analysis.Parasitology research · 2014Article
- Toxoplasmosis.Handbook of clinical neurology · 2013Article
- Identification of two novel coccidian species shed by California sea lions (Zalophus californianus).The Journal of parasitology · 2012Article
- Population genetics of Toxoplasma gondii: new perspectives from parasite genotypes in wildlife.Veterinary parasitology · 2011Review
- Discovery of three novel coccidian parasites infecting California sea lions (Zalophus californianus), with evidence of sexual replication and interspecies pathogenicity.The Journal of parasitology · 2011Article
- Polyparasitism is associated with increased disease severity in Toxoplasma gondii-infected marine sentinel species.PLoS neglected tropical diseases · 2011Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
Sarcocystis neurona is an apicomplexan parasite identified as a cause of fatal neurological disease in the threatened southern sea otter (Enhydra lutris nereis). In an effort to characterize virulent S. neurona strains circulating in the marine ecosystem, this study developed a range of markers relevant for molecular genotyping. Highly conserved sequences within the 18S ribosomal gene array, the plastid-encoded RNA polymerase (RPOb) and the cytochrome c oxidase subunit 1 mitochondrial gene (CO1) were assessed for their ability to distinguish isolates at the genus and species level. For within-species comparisons, five surface antigens (SnSAG1-SnSAG5) and one high resolution microsatellite marker (Sn9) were developed as genotyping markers to evaluate intra-strain diversity. Molecular analysis at multiple loci revealed insufficient genetic diversity to distinguish terrestrial isolates from strains infecting marine mammals. Furthermore, SnSAG specific primers applied against DNA from the closely related species, Sarcocystis falcatula, lead to the discovery of highly similar orthologs to SnSAG2, 3, and 4, calling into question the specificity of diagnostic tests based on these antigens. The results of this study suggest a population genetic structure for S. neurona similar to that reported for the related parasite, Toxoplasma gondii, dominated by a limited number of successful genotypes.
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Registered trials
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