Evidence map›Paper›PMID 20070316›Full record

ReviewClinical and experimental immunology2010

An approach to the diagnosis and management of systemic vasculitis.

A Miller, M Chan, A Wiik, S A Misbah, R A Luqmani

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Clinical characteristics of patients with granulomatosis with polyangiitis and microscopic polyangiitis in ENT practice: a comparative analysis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2018
    Article
  5. Article
  6. Article
  7. Article
  8. Non-invasive imaging of vascular inflammation.Frontiers in immunology · 2014
    Review
  9. In Vitro Global Gene Expression Analyses Support the Ethnopharmacological Use of Achyranthes aspera.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  10. Broadening the translational immunology landscape.Clinical and experimental immunology · 2012
    Article
  11. Review
  12. Immunomodulatory treatment of interstitial lung disease.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

A MillerNuffield Orthopaedic Centre, Oxford, UK.
M Chan
A Wiik
S A Misbah
R A Luqmani
Nuffield Orthopaedic Centre · GBChurchill Hospital · GBStatens Serum Institut · DKUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The systemic vasculitides are a complex and often serious group of disorders which, while uncommon, require careful management in order to ensure optimal outcome. In most cases there is no known cause. Multi-system disease is likely to be fatal without judicious use of immunosuppression. A prompt diagnosis is necessary to preserve organ function. Comprehensive and repeated disease assessment is a necessary basis for planning therapy and modification of treatment protocols according to response. Therapies typically include glucocorticoids and, especially for small and medium vessel vasculitis, an effective immunosuppressive agent. Cyclophosphamide is currently the standard therapy for small vessel multi-system vasculitis, but other agents are now being evaluated in large randomized trials. Comorbidity is common in patients with vasculitis, including the cumulative effects of potentially toxic therapy. Long-term evaluation of patients is important in order to detect and manage relapses.

Indexed as

AnimalsAntibodies, Antineutrophil CytoplasmicAutoantibodiesBiopsyClinical Trials as TopicDiagnostic ImagingDrug DesignEarly DiagnosisHumansImmunosuppressive AgentsIncidenceInflammation MediatorsInterdisciplinary CommunicationMiceMice, KnockoutMulticenter Studies as TopicAntibodies, Antineutrophil CytoplasmicAutoantibodiesImmunosuppressive AgentsInflammation Mediators

Identifiers

PMID20070316
PMCPMC2857937
OpenAlexW1489092077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.