ReviewAnnual review of public health2010
Family history in public health practice: a genomic tool for disease prevention and health promotion.
Review in Annual review of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
130 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Family history tools for primary care: A systematic review.The European journal of general practice · 2022Pooled it
- Efficacy and Safety of Morinda Officinalis Oligosaccharides Combined with Probiotics as a Therapeutic Strategy for Major Depressive Disorder with Gastrointestinal Symptoms: A Randomized, Double-Blind, Controlled Clinical Trial.Neuropsychiatric disease and treatment · 2025Trial
- Comparing models of delivery for cancer genetics services among patients receiving primary care who meet criteria for genetic evaluation in two healthcare systems: BRIDGE randomized controlled trial.BMC health services research · 2021Trial
- Communication Among Melanoma Family Members.Journal of health communication · 2017Trial
- Assessing family history of chronic disease in primary care: Prevalence, documentation, and appropriate screening.Canadian family physician Medecin de famille canadien · 2017Trial
- Family Ties: The Role of Family Context in Family Health History Communication About Cancer.Journal of health communication · 2016Trial
- Acceptability and feasibility of a virtual counselor (VICKY) to collect family health histories.Genetics in medicine : official journal of the American College of Medical Genetics · 2015Trial
- Impact of family history assessment on communication with family members and health care providers: A report from the Family Healthware™ Impact Trial (FHITr).Preventive medicine · 2015Trial
- The KinFact intervention - a randomized controlled trial to increase family communication about cancer history.Journal of women's health (2002) · 2014Trial
- Personalized Risk Estimator for Rheumatoid Arthritis (PRE-RA) Family Study: rationale and design for a randomized controlled trial evaluating rheumatoid arthritis risk education to first-degree relatives.Contemporary clinical trials · 2014Trial
- Telehealth personalized cancer risk communication to motivate colonoscopy in relatives of patients with colorectal cancer: the family CARE Randomized controlled trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Trial
- Family history assessment: impact on disease risk perceptions.American journal of preventive medicine · 2012Trial
- Correlates of family health history discussions between college students and physicians: does family cancer history make a difference?The journal of primary prevention · 2011Trial
- Cross-regulatory mechanisms linking ferroptosis, epigenetics, and circadian rhythm to mitochondrial quality control in diabetic cardiomyopathy.Journal of advanced research · 2026Review
- Evaluation of the genome-informed risk assessment (GIRA) approach from eMERGE in an independent health system.medRxiv : the preprint server for health sciences · 2026Article
- Evaluating the impact of family history and polygenic risk scores on cardiometabolic disease risk.BMC medicine · 2026Article
- Association between family history and onset age of cancer in China.Chinese medical journal · 2026Article
- Health Literacy and Awareness of Family Health History in the All of Us Research Program.Public health genomics · 2026Article
- Perceptions of family health history in an East Baltimore community.Journal of community genetics · 2025Article
- Preeclampsia prediction with maternal and paternal polygenic risk scores: the TMM BirThree Cohort Study.Scientific reports · 2025Article
70 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Family history is a risk factor for many chronic diseases, including cancer, cardiovascular disease, and diabetes. Professional guidelines usually include family history to assess health risk, initiate interventions, and motivate behavioral changes. The advantages of family history over other genomic tools include a lower cost, greater acceptability, and a reflection of shared genetic and environmental factors. However, the utility of family history in public health has been poorly explored. To establish family history as a public health tool, it needs to be evaluated within the ACCE framework (analytical validity; clinical validity; clinical utility; and ethical, legal, and social issues). Currently, private and public organizations are developing tools to collect standardized family histories of many diseases. Their goal is to create family history tools that have decision support capabilities and are compatible with electronic health records. These advances will help realize the potential of family history as a public health tool.
Indexed as
Identifiers
20070206What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.