Evidence map›Paper›PMID 20070197›Full record

ReviewAnnual review of public health2010

Ecogenomics of respiratory diseases of public health significance.

Stavros Garantziotis, David A Schwartz

Abstract readReview
In one paragraph

Review in Annual review of public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Allergic asthma: influence of genetic and environmental factors.The Journal of biological chemistry · 2011
    Review
  10. Review
  11. Effect of gene environment interactions on lung function and cardiovascular disease in COPD.International journal of chronic obstructive pulmonary disease · 2011
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Stavros GarantziotisClinical Research Program and Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA. Garantziotis@niehs.nih.gov
David A Schwartz
National Institute of Environmental Health Sciences · USUniversity of Colorado Denver · US

Funding

The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue InjuryZIAES102605 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GARANTZIOTIS, STAVROS · 2009 to 2025
$22.6M
The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue InjuryZ01ES102605 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GARANTZIOTIS, STAVROS · 2008 to 2008
$621k
Intramural NIH HHS Z01 ES102605Intramural NIH HHS ZIA ES102605
6 · The paper itself

Abstract

Gene-environment interactions are the indisputable cause of most respiratory diseases. However, we still have very limited understanding of the mechanisms that guide these interactions. Although the conceptual approaches to environmental genomics were established several decades ago, the tools are only now available to better define the mechanisms that underlie the interactions among these important etiological features of lung disease. In this article, we summarize recent insights in the environmental genomics (ecogenomics) of common nonmalignant respiratory diseases (asthma, COPD, pulmonary fibrosis, and respiratory infections), describe the framework of gene-environment interactions that inform the pathogenesis of respiratory diseases, and propose future research directions that will help translate scientific advances into public health gains.

Indexed as

MetagenomicsPublic HealthEpigenesis, GeneticGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansRespiratory Tract Diseases

Identifiers

PMID20070197
PMCPMC3402173
OpenAlexW2125786799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.