Evidence map›Paper›PMID 20069529›Full record

ArticleCurrent protocols in cytometry2010

Measurement of phagocytosis and of the phagosomal environment in polymorphonuclear phagocytes by flow cytometry.

Elizabeth R Simons

Abstract read
In one paragraph

Article in Current protocols in cytometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Elizabeth R SimonsBoston University School of Medicine, Boston, Massachusetts.

Funding

Functional Studies of Granulocyte MembranesR01HL076463 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SIMONS, ELIZABETH R · 2003 to 2007
$1.6M
FUNCTIONAL STUDIES OF GRANULOCYTE MEMBRANESR01DK031056 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SIMONS, ELIZABETH R · 1986 to 2003
$704k
NHLBI NIH HHS HL076463NHLBI NIH HHS R01 HL076463NIDDK NIH HHS DK31056
6 · The paper itself

Abstract

Phagocytes are the most important early components of the immune response, programmed to recognize, engulf, and destroy immune complexes (formed when antibodies recognize their specific antigens), foreign particles, bacteria, mycobacteria, apoptotic cells, etc. Neutrophils, monocytes, macrophages, and dendritic cells all participate in this process. Flow cytometry permits observation of phagocytes that have responded and, with the appropriate fluorescent probes, of the environment in the phagosome that has enclosed the foreign matter. This unit gives the background and the protocols for performing such studies.

Indexed as

Flow CytometryFluorescent DyesMycobacterium aviumPhagocytesPhagocytosisPhagosomesStaining and LabelingFluorescent Dyes

Identifiers

PMID20069529
PMCPMC2827611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.