Evidence map›Paper›PMID 20068571›Full record

ReviewNature reviews. Molecular cell biology2010

Mechanisms of chromosome behaviour during mitosis.

Claire E Walczak, Shang Cai, Alexey Khodjakov

Abstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Chromosome segregation synchrony inbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Repurposing Cell Cycle Oscillators for Multiciliated Cell Differentiation.Advances in experimental medicine and biology · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Assessment of Chromosome Congression Defects in Mammalian Oocytes.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  20. Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claire E WalczakMedical Sciences Program, Indiana University, Myers Hall 262, 915 East 3rd Street, Bloomington, Indiana, 47405, USA. cwalczak@indiana.edu
Shang Cai
Alexey Khodjakov

Funding

FUNCTIONAL PROPERTIES OF CENTROSOMES IN SOMATIC CELLSR01GM059363 · NIGMS · WADSWORTH CENTER · PI KHODJAKOV, ALEXEY L · 1999 to 2017
$6.3M
Mechanisms of Spindle AssemblyR01GM059618 · NIGMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WALCZAK, CLAIRE E · 1999 to 2016
$4.7M
NIGMS NIH HHS GM59363NIGMS NIH HHS GM59618NIGMS NIH HHS R01 GM059363NIGMS NIH HHS R01 GM059618
6 · The paper itself

Abstract

For over a century, scientists have strived to understand the mechanisms that govern the accurate segregation of chromosomes during mitosis. The most intriguing feature of this process, which is particularly prominent in higher eukaryotes, is the complex behaviour exhibited by the chromosomes. This behaviour is based on specific and highly regulated interactions between the chromosomes and spindle microtubules. Recent discoveries, enabled by high-resolution imaging combined with the various genetic, molecular, cell biological and chemical tools, support the idea that establishing and controlling the dynamic interaction between chromosomes and microtubules is a major factor in genomic fidelity.

Indexed as

Cell BiologyChromosomesMitosisAnimalsHumansMicrotubulesSpindle Apparatus

Identifiers

PMID20068571
PMCPMC2893392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.