Evidence map›Paper›PMID 20068255›Full record

Trial reportBMJ (Clinical research ed.)2010

Effectiveness of early physiotherapy to prevent lymphoedema after surgery for breast cancer: randomised, single blinded, clinical trial.

María Torres Lacomba, María José Yuste Sánchez, Alvaro Zapico Goñi, David Prieto Merino, Orlando Mayoral del Moral, Ester Cerezo Téllez, Elena Minayo Mogollón

3 registry-linked trialsOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 139 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 15 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03250351 nacompletednot on this mapstarted 2017, after this paper: background citation

Effectiveness of Nerve Mobilization Techniques at Improving Upper Limb Morbidity Following Breast Cancer Surgery

TypeinterventionalSponsorUniversity of AlcalaRan2017 to 2022Enrolled140ConditionsBreast Cancer FemaleArmsNeural mobilization group, Control group
NCT04731805 nacompletednot on this mapstarted 2012, after this paper: background citation

"Moving On" - A Randomized Controlled Trial for Acceptability and Feasibility of an Early Physical Therapy Education Intervention for Breast Cancer Surgical Candidates

TypeinterventionalSponsorNortheastern UniversityRan2012 to 2015Enrolled50ConditionsBreast CancerArmsMoving On After Breast Cancer
NCT07011316 recruitingnot on this mapstarted 2025, after this paper: background citation

Subclinical Assessment and Monitoring of Lymphatic System Function in Oncology Patients as Part of Physiotherapeutic Prevention of Limb Lymphoedema

TypeobservationalSponsorThe Greater Poland Cancer CentreRan2025 to 2029Enrolled600ConditionsLymphoedema
3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 15 syntheses or guidelines pooled it, 380 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Management of Axillary Web Syndrome after Breast Cancer: Evidence-Based Practice.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017
    Pooled it
  9. Pooled it
  10. A systematic review of axillary web syndrome (AWS).Journal of cancer survivorship : research and practice · 2015
    Pooled it
  11. Manual lymphatic drainage for lymphedema following breast cancer treatment.The Cochrane database of systematic reviews · 2015
    Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Exercise in patients with lymphedema: a systematic review of the contemporary literature.Journal of cancer survivorship : research and practice · 2011
    Pooled it
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

María Torres LacombaPhysiotherapy Department, School of Physiotherapy, Alcalá de Henares University, E-28871 Alcalá de Henares, Madrid, Spain. maria.torres@uah.es
María José Yuste Sánchez
Alvaro Zapico Goñi
David Prieto Merino
Orlando Mayoral del Moral
Ester Cerezo Téllez
Elena Minayo Mogollón
Universidad de Alcalá · ESComplejo Hospitalario Universitario de Toledo · ESLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effectiveness of early physiotherapy in reducing the risk of secondary lymphoedema after surgery for breast cancer.

designRandomised, single blinded, clinical trial.

settingUniversity hospital in Alcalá de Henares, Madrid, Spain.

participants120 women who had breast surgery involving dissection of axillary lymph nodes between May 2005 and June 2007.

interventionThe early physiotherapy group was treated by a physiotherapist with a physiotherapy programme including manual lymph drainage, massage of scar tissue, and progressive active and action assisted shoulder exercises. This group also received an educational strategy. The control group received the educational strategy only.

main outcome measureIncidence of clinically significant secondary lymphoedema (>2 cm increase in arm circumference measured at two adjacent points compared with the non-affected arm).

results116 women completed the one year follow-up. Of these, 18 developed secondary lymphoedema (16%): 14 in the control group (25%) and four in the intervention group (7%). The difference was significant (P=0.01); risk ratio 0.28 (95% confidence interval 0.10 to 0.79). A survival analysis showed a significant difference, with secondary lymphoedema being diagnosed four times earlier in the control group than in the intervention group (intervention/control, hazard ratio 0.26, 95% confidence interval 0.09 to 0.79).

conclusionEarly physiotherapy could be an effective intervention in the prevention of secondary lymphoedema in women for at least one year after surgery for breast cancer involving dissection of axillary lymph nodes.

trial registrationCurrent controlled trials ISRCTN95870846.

Indexed as

Physical Therapy ModalitiesArmAxillaBreast NeoplasmsFemaleHumansLymphatic MetastasisLymphedemaMiddle AgedPostoperative ComplicationsSingle-Blind MethodTreatment Outcome

Identifiers

PMID20068255
PMCPMC2806631
OpenAlexW1488738068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.