SynthesisBMC clinical pharmacology2010
Reporting randomised clinical trials of analgesics after traumatic or orthopaedic surgery is inadequate: a systematic review.
Synthesis in BMC clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Safety, Tolerability and Efficacy of Drugs for Treating Behavioural Insomnia in Children with Attention-Deficit/Hyperactivity Disorder: A Systematic Review with Methodological Quality Assessment.Paediatric drugs · 2017Pooled it
- Pooled it
- Consolidated standards of reporting trials (CONSORT) and the completeness of reporting of randomised controlled trials (RCTs) published in medical journals.The Cochrane database of systematic reviews · 2012Pooled it
- Pooled it
- Colloidal Silicon Dioxide in Tablet form (Carbowhite) Efficacy in Patients with Acute Diarrhea: Results of Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study.Scientific reports · 2020Trial
- Harms Reporting in the RCTs Underpinning the AAOS Clinical Practice Guidelines for Clavicle Fractures.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025Review
- Conducting Trial-Based Economic Evaluations Using R: A Tutorial.PharmacoEconomics · 2023Article
- Intervention Reporting of Published Trials Is Insufficient in Orthopaedic Surgery Journals: Application of the Template for Intervention Description and Replication Checklist.Arthroscopy, sports medicine, and rehabilitation · 2021Article
- The statistical approach in trial-based economic evaluations matters: get your statistics together!BMC health services research · 2021Article
- A methodological survey on reporting of pilot and feasibility trials for physiotherapy interventions: a study protocol.BMJ open · 2019Article
- The reporting of progression criteria in protocols of pilot trials designed to assess the feasibility of main trials is insufficient: a meta-epidemiological study.Pilot and feasibility studies · 2019Article
- Levodopa-Carbidopa Intestinal Gel in Parkinson's Disease: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2018Article
- Systematic review of acute physically active learning and classroom movement breaks on children's physical activity, cognition, academic performance and classroom behaviour: understanding critical design features.BMJ open sport & exercise medicine · 2018Article
- Does the medical literature remain inadequately described despite having reporting guidelines for 21 years? - A systematic review of reviews: an update.Journal of multidisciplinary healthcare · 2018Review
- Article
- How to do random allocation (randomization).Clinics in orthopedic surgery · 2014Article
- Risk of bias of randomized controlled trials published in orthopaedic journals.BMC medical research methodology · 2013Article
- Why perform a priori sample size calculation?Canadian journal of surgery. Journal canadien de chirurgie · 2013Article
- A systematic scoping review of adherence to reporting guidelines in health care literature.Journal of multidisciplinary healthcare · 2013Article
- Improvement of quality of reporting in randomised controlled trials to prevent hypotension after spinal anaesthesia for caesarean section.Gynecological surgery · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral randomised clinical trials (RCTs) of analgesics in postoperative pain after traumatic or orthopaedic surgery (TOS) have been published, but no studies have assessed the quality of these reports. We aimed to examine the quality of reporting RCTs on analgesics for postoperative pain after TOS.
methodsReports of RCTs assessing analgesics in postoperative pain after TOS were systematically searched from electronic databases. The quality of reports was assessed using the CONSORT checklist (scoring range from 0 to 22). The quality was considered poor when scoring was 12 or lesser. The publication year and the impact factor of journals were recorded.
resultsA total of 92 reports of RCTs were identified and 69 (75%) scored 12 or lesser in CONSORT checklist (range 5-17). The mean (SD) CONSORT score of all reports was 10.6 (2.7). Missing CONSORT items included primary and secondary outcome measures (11%), the specific objectives and hypothesis definition (12%), the sample size calculation (12%), the dates defining the periods of recruitment (12%), the discussion of external validity of findings (14%), the allocation sequence generation (24%), and the interpretation of potential bias or imprecision of results (25%). There was a little improvement in CONSORT scores over time (r = 0.62; p < 0.001) and with impact factor of journals (r = 0.30; p < 0.001).
conclusionQuality of reporting RCTs on analgesics after TOS is poor. Reporting of those RCTs should be improved according to methodological standard checklists in the next years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.