ArticleInternational urogynecology journal2010
Retrospective chart review of vaginal diazepam suppository use in high-tone pelvic floor dysfunction.
Article in International urogynecology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Interventional treatment for myofascial pelvic floor pain in women: systematic review with meta-analysis.International urogynecology journal · 2021Pooled it
- A pilot randomized trial of levator injections versus physical therapy for treatment of pelvic floor myalgia and sexual pain.International urogynecology journal · 2015Trial
- Intra-vaginal diazepam for high-tone pelvic floor dysfunction: a randomized placebo-controlled trial.International urogynecology journal · 2013Trial
- Evaluation of the Effectiveness of Combined Treatment with Intravaginal Diazepam and Pelvic Floor Rehabilitation in Patients with Vulvodynia by Ultrasound Monitoring of Biometric Parameters of Pelvic Muscles: A Pilot Study.Diseases (Basel, Switzerland) · 2024Article
- Female Sexual Dysfunctions and Urogynecological Complaints: A Narrative Review.Medicina (Kaunas, Lithuania) · 2022Review
- Clinical Management of Chronic Pelvic Pain in Endometriosis Unresponsive to Conventional Therapy.Journal of personalized medicine · 2022Article
- Managing Interstitial Cystitis/Bladder Pain Syndrome in Older Adults.Drugs & aging · 2021Review
- A practical guide to female sexual dysfunction: An evidence-based review for physicians in Canada.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018Review
- Sexual Dysfunction and Intimacy for Ostomates.Clinics in colon and rectal surgery · 2017Review
- Physical, Complementary, and Alternative Medicine in the Treatment of Pelvic Floor Disorders.Current urology reports · 2017Review
- Review
- Female Sexual Dysfunction: Is It a Treatable Disease?Current urology reports · 2016Review
- Bladder outlet obstruction in women: functional causes.Current urology reports · 2014Review
- Innovative Approach for Interstitial Cystitis: Vaginal Pessaries Loaded Diazepam-A Preliminary Study.Journal of pharmaceutics · 2013Article
- Evaluation and management of outlet obstruction in women without anatomical abnormalities on physical exam or cystoscopy.Current urology reports · 2012Review
- Hysteropexy compared to hysterectomy for uterine prolapse surgery: does durability differ?International urogynecology journal · 2012Article
- Review
- Myotonometry Reliably Measures Muscle Stiffness in the Thenar and Perineal Muscles.Physiotherapy Canada. Physiotherapie CanadaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To study intravaginal diazepam suppositories as adjunctive treatment for high-tone pelvic floor dysfunction (HTPFD) and sexual pain. A retrospective chart review was conducted on 26 patients who received diazepam suppositories as adjuvant therapy to pelvic physical therapy and intramuscular trigger point injections for bladder pain, sexual pain, and levator hypertonus. Pelvic floor muscular tone and pain were assessed by palpation and perineometry; sexual pain was objectively rated by Female Sexual Function Index (FSFI) and the Visual Analog Scale for Pain (VAS-P). Twenty-five out of 26 patients reported subjective improvement with suppository use; six out of seven sexually active patients resumed intercourse. Sexual pain as assessed on FSFI and serial VAS-P improved with diazepam (by 1.44 on 10-point scale, p = 0.14). PFM tone improved during resting (p < 0.001), squeezing (p = 0.014), and relaxation (p = 0.003) phases. Vaginal diazepam suppositories gave a clinically significant improvement in the treatment of HTPFD compared with the usual treatment regimen alone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.