ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2009
Stem cells, inflammation and allergy.
Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Review
- Recent advances of eosinophils and its correlated diseases.Frontiers in public health · 2022Review
- Redistribution, homing and organ-invasion of neoplastic stem cells in myeloid neoplasms.Seminars in cancer biology · 2020Review
- Inflammation Shapes Stem Cells and Stemness during Infection and Beyond.Frontiers in cell and developmental biology · 2016Review
- Alleviation of skin inflammation after Lin(-) cell transplantation correlates with their differentiation into myeloid-derived suppressor cells.Scientific reports · 2015Article
- In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces.Mucosal immunology · 2015Review
- A case of eosinophilic fasciitis presenting as pitting edema of the lower extremities.Allergy, asthma & immunology research · 2014Article
- Generation and Characterization of Anti-CD34 Monoclonal Antibodies that React with Hematopoietic Stem Cells.Cell journal · 2014Article
- Gene-Gene Interaction Between CCR3 and Eotaxin Genes: The Relationship With Blood Eosinophilia in Asthma.Allergy, asthma & immunology research · 2014Article
- Hematopoietic stem and progenitor cells in inflammation and allergy.Frontiers in immunology · 2013Review
- Therapeutic role of hematopoietic stem cells in autism spectrum disorder-related inflammation.Frontiers in immunology · 2013Article
- PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Hematopoietic stem and progenitor cells as effectors in innate immunity.Bone marrow research · 2012Article
- CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.Stem cells (Dayton, Ohio) · 2011Article
- Local proliferation and mobilization of CCR3(+) CD34(+) eosinophil-lineage-committed cells in the lung.Immunology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, many studies have suggested a potential role for early hematopoietic progenitor cell and hematopoietic stem cell (HSC) recruitment and differentiation in the development of allergy and inflammation. This is based largely on evidence that stem cells or CD34+ progenitor cells are recruited to the site of inflammation in allergic diseases, likely through many of the same adhesion and chemokine receptors used for stem cell homing to the bone marrow (PSGL-1, CXCL12, alpha4-beta1 integrin, CD44, etc). Once at the site of inflammation, it has been suggested that stem cells could participate in the perpetuation of inflammation by maturing, locally, into inflammatory cells in response to the growth factors released in situ. Here we provide a brief review of the evidence to suggest that hematopoietic stem and progenitor cells (versus mature hematopoietic lineages) are, indeed, recruited to the site of allergic inflammation. We also discuss the molecules that likely play a role in this process, and highlight a number of our novel observations on a specific role for the stem cell antigen CD34 in this process.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.