Evidence map›Paper›PMID 20066116›Full record

ReviewCold Spring Harbor perspectives in biology2009

Membrane organization and dynamics in cell polarity.

Kelly Orlando, Wei Guo

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. The Journal of cell biology · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kelly OrlandoDepartment of Biology, University of Pennsylvania, Philadelphia, 19104-6018, USA.
Wei Guo

Funding

The Role of the Exocyst in Cell MigrationR01GM085146 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GUO, WEI · 2009 to 2020
$4.1M
Spatial regulation of exocytosisR01GM064690 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GUO, WEI · 2002 to 2012
$2.5M
NIGMS NIH HHS R01 GM064690NIGMS NIH HHS R01 GM085146
6 · The paper itself

Abstract

The establishment and maintenance of cell polarity is important to a wide range of biological processes ranging from chemotaxis to embryogenesis. An essential feature of cell polarity is the asymmetric organization of proteins and lipids in the plasma membrane. In this article, we discuss how polarity regulators such as small GTP-binding proteins and phospholipids spatially and kinetically control vesicular trafficking and membrane organization. Conversely, we discuss how membrane trafficking contributes to cell polarization through delivery of polarity determinants and regulators to the plasma membrane.

Indexed as

Cell PolarityAnimalsCadherinscdc42 GTP-Binding ProteinCell MembraneChemotaxisDictyosteliumDrosophila melanogasterExocytosisKineticsLipidsModels, Biologicalrab GTP-Binding Proteinsrho GTP-Binding ProteinsCadherinscdc42 GTP-Binding ProteinLipidsrab GTP-Binding Proteinsrho GTP-Binding Proteins

Identifiers

PMID20066116
PMCPMC2773647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.