Evidence map›Paper›PMID 20066098›Full record

ReviewCold Spring Harbor perspectives in biology2009

Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.

Pierre D McCrea, Dongmin Gu, Maria S Balda

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 89 citations in OpenAlex.

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  12. Redox Role ofFrontiers in immunology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Pierre D McCreaDepartment of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Program in Genes and Development, University of Texas Graduate School of Biomedical Sciences, Houston, Texas 77030, USA. pdmccrea@mdanderson.org
Dongmin Gu
Maria S Balda
The University of Texas MD Anderson Cancer Center · USUniversity College London · GB

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
p120-catenin sub-family functionsR01GM052112 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MCCREA, PIERRE D · 1995 to 2010
$3.5M
Biotechnology and Biological Sciences Research CouncilMedical Research Council G0400678NCI NIH HHS CA-16672NCI NIH HHS P30 CA016672NIGMS NIH HHS R01 GM052112NIGMS NIH HHS R01GM52112Wellcome Trust
6 · The paper itself

Abstract

Cell-cell junctions continue to capture the interest of cell and developmental biologists, with an emerging area being the molecular means by which junctional signals relate to gene activity in the nucleus. Although complexities often arise in determining the direct versus indirect nature of such signal transduction, it is clear that such pathways are essential for the function of tissues and that alterations may contribute to many pathological outcomes. This review assesses a variety of cell-cell junction-to-nuclear signaling pathways, and outlines interesting areas for further study.

Indexed as

Cell CommunicationGene Expression RegulationAnimalsCateninsCell NucleusDesmosomesDevelopmental BiologyHumansIntercellular JunctionsModels, BiologicalPhosphatidylinositol 3-KinasesPlakophilinsReceptor Protein-Tyrosine KinasesSignal TransductionCateninsPhosphatidylinositol 3-KinasesPlakophilinsReceptor Protein-Tyrosine Kinases

Identifiers

PMID20066098
PMCPMC2773621
OpenAlexW2152698912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.