Evidence map›Paper›PMID 20066082›Full record

ReviewCold Spring Harbor perspectives in biology2009

Widely conserved signaling pathways in the establishment of cell polarity.

Luke Martin McCaffrey, Ian G Macara

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Mechanisms of polarity protein expression control.Current opinion in cell biology · 2016
    Review
  14. Establishing and maintaining cell polarity with mRNA localization in Drosophila.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016
    Review
  15. Influence of cell polarity on early development of the sea urchin embryo.Developmental dynamics : an official publication of the American Association of Anatomists · 2015
    Article
  16. Article
  17. Article
  18. The Polarity Protein Pals1 Regulates Radial Sorting of Axons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Luke Martin McCaffreyDepartment of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908-5077, USA.
Ian G Macara

Funding

MECHANISMS OF CELL POLARITY ESTABLISHMENTR01GM070902 · NIGMS · VANDERBILT UNIVERSITY · PI MACARA, IAN G · 2004 to 2022
$5.4M
CIHRNIGMS NIH HHS GM090702NIGMS NIH HHS R01 GM070902
6 · The paper itself

Abstract

How are the asymmetric distributions of proteins, lipids, and RNAs established and maintained in various cell types? Studies from diverse organisms show that Par proteins, GTPases, kinases, and phosphoinositides participate in conserved signaling pathways to establish and maintain cell polarity.

Indexed as

Cell PolaritySignal TransductionAnimalsCell LineageDrosophilaGTP PhosphohydrolasesHumansModels, BiologicalPhenotypeProtein IsoformsRNA, MessengerGTP PhosphohydrolasesProtein IsoformsRNA, Messenger

Identifiers

PMID20066082
PMCPMC2742088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.