Evidence map›Paper›PMID 20065941›Full record

ReviewNature reviews. Microbiology2010

Microbial threat lists: obstacles in the quest for biosecurity?

Arturo Casadevall, David A Relman

Abstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A century of assessment: A systematic review of biothreat risk assessments.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Pooled it
  2. Trimming tiers - Motivations and means for de-risking select agents.Frontiers in bioengineering and biotechnology · 2025
    Article
  3. [Visual diagnosis for experts].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Pathogen security-help or hindrance?Frontiers in bioengineering and biotechnology · 2014
    Review
  12. Article
  13. The future of biological warfare.Microbial biotechnology · 2012
    Article
  14. Article
  15. Article
  16. Article
  17. Destruction of microbial collections in response to select agent and toxin list regulations.Biosecurity and bioterrorism : biodefense strategy, practice, and science · 2010
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arturo CasadevallDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, New York 10461, USA. casadeva@aecom.yu.edu
David A Relman

Funding

Viral Pathogenesis and TherapeuticsU54AI057158 · NIAID · WADSWORTH CENTER · PI LIPKIN, W. IAN · 2003 to 2014
$100.8M
NIAID NIH HHS 2U54AI057158-06NIAID NIH HHS U54 AI057158
6 · The paper itself

Abstract

Anxiety about threats from the microbial world and about the deliberate misuse of microorganisms has led to efforts to define and control these dangers using lists and regulations. One list with tremendous legal implications and a potentially huge impact on research is the Select Agents and Toxins List, which was created by the US Government to limit the possession of and access to particular microorganisms and toxins. In this article, in addition to highlighting general problems with taxonomy-based, microorganism-centric lists, we discuss our view that such lists may have the paradoxical effect of increasing the societal vulnerability to biological attack and natural epidemics by interfering with the sharing of microbial samples and hindering research on vaccines and therapeutics.

Indexed as

AnimalsBacillus anthracisBacteriaBioterrorismHumansPubMedSecurity MeasuresToxins, BiologicalUnited StatesVirusesToxins, Biological

Identifiers

PMID20065941
PMCPMC7097391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.