Evidence map›Paper›PMID 20065056›Full record

ArticleAntimicrobial agents and chemotherapy2010

GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.

S D Kotsakis, C C Papagiannitsis, E Tzelepi, N J Legakis, V Miriagou, L S Tzouvelekis

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Novel Insights intoMicrobiology spectrum · 2022
    Article
  2. Laboratory Variants GESAntimicrobial agents and chemotherapy · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Osteomyelitis due to multiple carbapenemase-producing Gram-negative bacteria: The first case report of a GES-13-producing Pseudomonas aeruginosa isolate in Canada.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2014
    Article
  7. Article
  8. Article
  9. Article
  10. Pseudomonas aeruginosa: resistance to the max.Frontiers in microbiology · 2011
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

S D KotsakisLaboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
C C Papagiannitsis
E Tzelepi
N J Legakis
V Miriagou
L S Tzouvelekis
Institut Pasteur · FRPasteur Hellenic Institute · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GES-13 beta-lactamase, a novel GES variant possessing Lys-104 and Asn-170, was identified in Pseudomonas aeruginosa. bla(GES-13) was the single gene cassette of a class 1 integron probably located in the chromosome. GES-13 efficiently hydrolyzed broad-spectrum cephalosporins and aztreonam. Imipenem was a potent inhibitor of GES-13 but was not hydrolyzed at measurable rates.

Indexed as

beta-LactamasesGenetic VariationAnti-Bacterial AgentsAztreonambeta-LactamsCephalosporinsHumansIntegronsMicrobial Sensitivity TestsMolecular Sequence DataPseudomonas aeruginosaPseudomonas InfectionsSequence Analysis, DNAAnti-Bacterial AgentsAztreonambeta-Lactamasesbeta-LactamsCephalosporins

Identifiers

PMID20065056
PMCPMC2825989
OpenAlexW2117172622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.