Trial reportJournal of the American Medical Informatics Association : JAMIA
The impact of computerized provider order entry on medication errors in a multispecialty group practice.
Trial report in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Digital Health Technology Interventions for Improving Medication Safety: Systematic Review of Economic Evaluations.Journal of medical Internet research · 2025Pooled it
- Risks to patient safety associated with implementation of electronic applications for medication management in ambulatory care--a systematic review.BMC medical informatics and decision making · 2013Pooled it
- Barriers and facilitators to implementing electronic prescription: a systematic review of user groups' perceptions.Journal of the American Medical Informatics Association : JAMIAPooled it
- Usability of a perioperative medication-related clinical decision support software application: a randomized controlled trial.Journal of the American Medical Informatics Association : JAMIA · 2022Trial
- Transitioning between electronic health records: effects on ambulatory prescribing safety.Journal of general internal medicine · 2011Trial
- Effects of an online personal health record on medication accuracy and safety: a cluster-randomized trial.Journal of the American Medical Informatics Association : JAMIATrial
- Assessing the Satisfaction of Physicians in Using the Electronic Prescription System of Social Security in Iran: A Cross-Sectional Study.Health science reports · 2025Article
- Effectiveness of Quality Use of Medicines (QUM) Programs and Strategies in Saudi Arabia: A Narrative Review.Drug, healthcare and patient safety · 2025Review
- Pediatric Sedation Assessment and Management System (PSAMS) for Pediatric Sedation in China: Development and Implementation Report.JMIR medical informatics · 2024Article
- "Are we there yet?" Ten persistent hazards and inefficiencies with the use of medication administration technology from the perspective of practicing nurses.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- How would final-year medical students perform if their skill-based prescription assessment was real life?British journal of clinical pharmacology · 2022Article
- Effects of Guideline-based Computerized Provider Order Entry Systems on the Chemotherapy Order Process: a Systematic Review.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2022Review
- Development of a Perioperative Medication-Related Clinical Decision Support Tool to Prevent Medication Errors: An Analysis of User Feedback.Applied clinical informatics · 2021Article
- ChemoPalRx-A Mobile App That Enhances Chemotherapy Prescription Accuracy: A Cross-Sectional Study.JCO clinical cancer informatics · 2021Article
- Analysis and outcomes of wrong site thyroid surgery.BMC surgery · 2021Article
- Digital Health in Physicians' and Pharmacists' Office: A Comparative Study of e-Prescription Systems' Architecture and Digital Security in Eight Countries.Omics : a journal of integrative biology · 2021Review
- Clinical decision support systems-based interventions to improve medication outcomes: A systematic literature review on features and effects.Medical journal of the Islamic Republic of Iran · 2021Review
- Economic impact of clinical decision support interventions based on electronic health records.BMC health services research · 2020Review
- A Quality Improvement Initiative to Decrease Platelet Ordering Errors and a Proposed Model for Evaluating Clinical Decision Support Effectiveness.Applied clinical informatics · 2019Article
- Interventions to reduce the prescription of inappropriate medicines in older patients.Revista de saude publica · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveComputerized provider order entry (CPOE) has been shown to improve patient safety by reducing medication errors and subsequent adverse drug events (ADEs). Studies demonstrating these benefits have been conducted primarily in the inpatient setting, with fewer in the ambulatory setting. The objective was to evaluate the effect of a basic, ambulatory CPOE system on medication errors and associated ADEs.
designThis quasiexperimental, pretest-post-test study was conducted in a community-based, multispecialty health system not affiliated with an academic medical center. The intervention was a basic CPOE system with limited clinical decision support capabilities. MEASUREMENT: Comparison of prescriptions written before (n=5016 handwritten) to after (n=5153 electronically prescribed) implementation of the CPOE system. The primary outcome was the occurrence of error(s); secondary outcomes were types and severity of errors.
resultsFrequency of errors declined from 18.2% to 8.2%-a reduction in adjusted odds of 70% (OR: 0.30; 95% CI 0.23 to 0.40). The largest reductions were seen in adjusted odds of errors of illegibility (97%), use of inappropriate abbreviations (94%) and missing information (85%). There was a 57% reduction in adjusted odds of errors that did not cause harm (potential ADEs) (OR 0.43; 95% CI 0.38 to 0.49). The reduction in the number of errors that caused harm (preventable ADEs) was not statistically significant, perhaps due to few errors in this category.
conclusionsA basic CPOE system in a community setting was associated with a significant reduction in medication errors of most types and severity levels.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.