SynthesisJournal of the American Medical Informatics Association : JAMIA
Computerized clinical decision support for prescribing: provision does not guarantee uptake.
Synthesis in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
139 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Barriers and facilitators to the implementation and adoption of computerised clinical decision support systems: an overview of reviews.Systematic reviews · 2026Pooled it
- The effects of information technology interventions for optimizing antibiotic prescribing in urinary tract infections: a systematic review.BMC infectious diseases · 2025Pooled it
- Understanding "Alert Fatigue" in Primary Care: Qualitative Systematic Review of General Practitioners Attitudes and Experiences of Clinical Alerts, Prompts, and Reminders.Journal of medical Internet research · 2025Pooled it
- Design, effectiveness, and economic outcomes of contemporary chronic disease clinical decision support systems: a systematic review and meta-analysis.Journal of the American Medical Informatics Association : JAMIA · 2022Pooled it
- The use of electronic alerts in primary care computer systems to identify the excessive prescription of short-acting betaNPJ primary care respiratory medicine · 2018Pooled it
- A systematic review of near real-time and point-of-care clinical decision support in anesthesia information management systems.Journal of clinical monitoring and computing · 2017Pooled it
- Collaborative writing applications in healthcare: effects on professional practice and healthcare outcomes.The Cochrane database of systematic reviews · 2017Pooled it
- Precision diagnosis: a view of the clinical decision support systems (CDSS) landscape through the lens of critical care.Journal of clinical monitoring and computing · 2017Pooled it
- Factors that influence the implementation of e-health: a systematic review of systematic reviews (an update).Implementation science : IS · 2016Pooled it
- The impact of eHealth on the quality and safety of health care: a systematic overview.PLoS medicine · 2011Pooled it
- Barriers and Facilitators to the Use of Clinical Decision Support Systems in Primary Care: A Mixed-Methods Systematic Review.Annals of family medicinePooled it
- Patterns of CDSS adoption in primary care: a cluster analysis and predictive modelling study from a stepped wedge trial.Implementation science : IS · 2026Trial
- Trial
- Delivery of Lung-protective Ventilation for Acute Respiratory Distress Syndrome: A Hybrid Implementation-Effectiveness Trial.Annals of the American Thoracic Society · 2023Trial
- Increasing uptake of NHS Health Checks: a randomised controlled trial using GP computer prompts.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Trial
- Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care - A cluster-randomised clinical trial.BMC geriatrics · 2020Trial
- Factors Affecting Prescriber Implementation of Computer-Generated Medication Recommendations in the SENATOR Trial: A Qualitative Study.Drugs & aging · 2020Trial
- What drives adoption of a computerised, multifaceted quality improvement intervention for cardiovascular disease management in primary healthcare settings? A mixed methods analysis using normalisation process theory.Implementation science : IS · 2018Trial
- A Mobile Computerized Decision Support System to Prevent Hypoglycemia in Hospitalized Patients With Type 2 Diabetes Mellitus.Journal of diabetes science and technology · 2017Trial
- Implementing an evidence-based computerized decision support system to improve patient care in a general hospital: the CODES study protocol for a randomized controlled trial.Implementation science : IS · 2016Trial
79 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is wide variability in the use and adoption of recommendations generated by computerized clinical decision support systems (CDSSs) despite the benefits they may bring to clinical practice. We conducted a systematic review to explore the barriers to, and facilitators of, CDSS uptake by physicians to guide prescribing decisions. We identified 58 studies by searching electronic databases (1990-2007). Factors impacting on CDSS use included: the availability of hardware, technical support and training; integration of the system into workflows; and the relevance and timeliness of the clinical messages. Further, systems that were endorsed by colleagues, minimized perceived threats to professional autonomy, and did not compromise doctor-patient interactions were accepted by users. Despite advances in technology and CDSS sophistication, most factors were consistently reported over time and across ambulatory and institutional settings. Such factors must be addressed when deploying CDSSs so that improvements in uptake, practice and patient outcomes may be achieved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.