ArticleEnvironmental health perspectives2010
Microwaves from Mobile Phones Inhibit 53BP1 Focus Formation in Human Stem Cells More Strongly Than in Differentiated Cells: Possible Mechanistic Link to Cancer Risk.
Article in Environmental health perspectives, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
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- Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance.BioImpacts : BI · 2024Review
- Article
- A primary study on rat fetal development and brain-derived neurotrophic factor levels under the control of electromagnetic fields.Journal of public health in Africa · 2023Article
- Scientific evidence invalidates health assumptions underlying the FCC and ICNIRP exposure limit determinations for radiofrequency radiation: implications for 5G.Environmental health : a global access science source · 2022Article
- Article
- Microwaves from mobile phone induce reactive oxygen species but not DNA damage, preleukemic fusion genes and apoptosis in hematopoietic stem/progenitor cells.Scientific reports · 2019Article
- Radiofrequency radiation from nearby mobile phone base stations-a case comparison of one low and one high exposure apartment.Oncology letters · 2019Article
- Significant Cellular Viability Dependence on Time Exposition at ELF-EMF and RF-EMF In Vitro Studies.International journal of environmental research and public health · 2019Article
- The Effect of Prenatal Exposure to 2.4 GHz Radio Frequency on the Histology and Expression of the osteocalcin and RUNX2 Gene of the Forelimb in an NMRI Mouse.Journal of lasers in medical sciences · 2019Article
- Radiofrequency radiation from nearby base stations gives high levels in an apartment in Stockholm, Sweden: A case report.Oncology letters · 2018Article
- World Health Organization, radiofrequency radiation and health - a hard nut to crack (Review).International journal of oncology · 2017Review
- High radiofrequency radiation at Stockholm Old Town: An exposimeter study including the Royal Castle, Supreme Court, three major squares and the Swedish Parliament.Molecular and clinical oncology · 2017Article
- Measurements of Radiofrequency Radiation with a Body-Borne Exposimeter in Swedish Schools with Wi-Fi.Frontiers in public health · 2017Article
- Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study.Journal of biomedical physics & engineering · 2016Article
- Radiofrequency radiation at Stockholm Central Railway Station in Sweden and some medical aspects on public exposure to RF fields.International journal of oncology · 2016Article
- Effects of pulsed 2.856 GHz microwave exposure on BM-MSCs isolated from C57BL/6 mice.PloS one · 2015Article
- New Zealand adolescents' cellphone and cordless phone user-habits: are they at increased risk of brain tumours already? A cross-sectional study.Environmental health : a global access science source · 2013Article
- Cellular neoplastic transformation induced by 916 MHz microwave radiation.Cellular and molecular neurobiology · 2012Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is widely accepted that DNA double-strand breaks (DSBs) and their misrepair in stem cells are critical events in the multistage origination of various leukemias and tumors, including gliomas.
objectivesWe studied whether microwaves from mobile telephones of the Global System for Mobile Communication (GSM) and the Universal Global Telecommunications System (UMTS) induce DSBs or affect DSB repair in stem cells.
methodsWe analyzed tumor suppressor TP53 binding protein 1 (53BP1) foci that are typically formed at the sites of DSB location (referred to as DNA repair foci) by laser confocal microscopy.
resultsMicrowaves from mobile phones inhibited formation of 53BP1 foci in human primary fibroblasts and mesenchymal stem cells. These data parallel our previous findings for human lymphocytes. Importantly, the same GSM carrier frequency (915 MHz) and UMTS frequency band (1947.4 MHz) were effective for all cell types. Exposure at 905 MHz did not inhibit 53BP1 foci in differentiated cells, either fibroblasts or lymphocytes, whereas some effects were seen in stem cells at 905 MHz. Contrary to fibroblasts, stem cells did not adapt to chronic exposure during 2 weeks.
conclusionsThe strongest microwave effects were always observed in stem cells. This result may suggest both significant misbalance in DSB repair and severe stress response. Our findings that stem cells are most sensitive to microwave exposure and react to more frequencies than do differentiated cells may be important for cancer risk assessment and indicate that stem cells are the most relevant cellular model for validating safe mobile communication signals.
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