Evidence map›Paper›PMID 20064459›Full record

ReviewMolecular cell2009

Shifting players and paradigms in cell-specific transcription.

Joseph A D'Alessio, Kevin J Wright, Robert Tjian

Abstract readReview
In one paragraph

Review in Molecular cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Transcriptional profiling reveals signatures of latent developmental potential inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Expansion and Functional Diversification of TFIIB-Like Factors in Plants.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph A D'AlessioHoward Hughes Medical Institute, University of California, Berkeley, 94720, USA.
Kevin J Wright
Robert Tjian

Funding

THE SV40 TUMOR ANTIGENR37CA025417 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI TJIAN, ROBERT TSE NAN · 1987 to 2013
$6.8M
Structure and Function of Transcription ComplexesP01CA112181 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI TJIAN, ROBERT TSE NAN · 2005 to 2009
$5.7M
Howard Hughes Medical InstituteNCI NIH HHS P01 CA112181NCI NIH HHS R37 CA025417
6 · The paper itself

Abstract

Historically, developmental-stage- and tissue-specific patterns of gene expression were assumed to be determined primarily by DNA regulatory sequences and their associated activators, while the general transcription machinery including core promoter recognition complexes, coactivators, and chromatin modifiers was held to be invariant. New evidence suggests that significant changes in these general transcription factors including TFIID, BAF, and Mediator may facilitate global changes in cell-type-specific transcription.

Indexed as

Gene Expression Regulation, DevelopmentalTranscription, GeneticAnimalsMediator ComplexModels, MolecularPromoter Regions, GeneticProtein IsoformsTATA Box Binding Protein-Like ProteinsTissue DistributionTranscription Factor TFIIDMediator ComplexProtein IsoformsTATA Box Binding Protein-Like ProteinsTranscription Factor TFIID

Identifiers

PMID20064459
PMCPMC2807468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.