Evidence map›Paper›PMID 20064053›Full record

SynthesisJournal of athletic training

Quadriceps activation following knee injuries: a systematic review.

Joseph M Hart, Brian Pietrosimone, Jay Hertel, Christopher D Ingersoll

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of athletic training. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05568784 (Quadriceps Activation Comparative Analysis Based on Positioning of the Ankle During Supine Straight Leg Raise and Quad Set), which is not on this map. Cited by 184 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05568784 unknown statusnot on this map

Quadriceps Activation Comparative Analysis Based on Positioning of the Ankle During Supine Straight Leg Raise and Quad Set

TypeobservationalSponsorAndrews Research & Education FoundationRan2021 to 2024Enrolled100ConditionsQuadriceps Muscle Atrophy, Leg InjuryArmsStraight Leg Raise exercise
3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joseph M HartUniversity of Virginia, Charlottesville, VA 22908-0159, USA. jmh3zf@virginia.edu
Brian Pietrosimone
Jay Hertel
Christopher D Ingersoll

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextArthrogenic muscle inhibition is an important underlying factor in persistent quadriceps muscle weakness after knee injury or surgery.

objectiveTo determine the magnitude and prevalence of volitional quadriceps activation deficits after knee injury. DATA SOURCES: Web of Science database. STUDY SELECTION: Eligible studies involved human participants and measured quadriceps activation using either twitch interpolation or burst superimposition on patients with knee injuries or surgeries such as anterior cruciate ligament deficiency (ACLd), anterior cruciate ligament reconstruction (ACLr), and anterior knee pain (AKP). DATA EXTRACTION: Means, measures of variability, and prevalence of quadriceps activation (QA) failure (<95%) were recorded for experiments involving ACLd (10), ACLr (5), and AKP (3). DATA SYNTHESIS: A total of 21 data sets from 18 studies were initially identified. Data from 3 studies (1 paper reporting data for both ACLd and ACLr, 1 on AKP, and the postarthroscopy paper) were excluded from the primary analyses because only graphical data were reported. Of the remaining 17 data sets (from 15 studies), weighted mean QA in 352 ACLd patients was 87.3% on the involved side, 89.1% on the uninvolved side, and 91% in control participants. The QA failure prevalence ranged from 0% to 100%. Weighted mean QA in 99 total ACLr patients was 89.2% on the involved side, 84% on the uninvolved side, and 98.5% for the control group, with prevalence ranging from 0% to 71%. Thirty-eight patients with AKP averaged 78.6% on the involved side and 77.7% on the contralateral side. Bilateral QA failure was commonly reported in patients.

conclusionsQuadriceps activation failure is common in patients with ACLd, ACLr, and AKP and is often observed bilaterally.

Indexed as

Anterior Cruciate Ligament InjuriesLegMuscle StrengthAnterior Cruciate LigamentDatabases, FactualHumansKnee InjuriesPatellofemoral Pain SyndromePrevalenceQuadriceps Muscle

Identifiers

PMID20064053
PMCPMC2808760

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.