ArticleJournal of molecular histology2009
Interstitial Cajal-like cells of human Fallopian tube express estrogen and progesterone receptors.
Article in Journal of molecular histology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 88 citations in OpenAlex.
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- Telocytes in the Female Reproductive System: Up-to-Date Knowledge, Challenges and Possible Clinical Applications.Life (Basel, Switzerland) · 2022Review
- Telocytes and Their Structural Relationships With the Sperm Storage Tube and Surrounding Cell Types in the Utero-Vaginal Junction of the Chicken.Frontiers in veterinary science · 2022Article
- Oviductal Telocytes in Patients with Uterine Myoma.Biomedicines · 2021Article
- Ultrastructural evidence for telocytes in equine tendon.Journal of anatomy · 2021Article
- Distribution of estrogen receptor in the rabbit cervix during pregnancy with special reference to stromal elements: an immunohistochemical study.Scientific reports · 2020Article
- The Telocytes: Ten Years after Their Introduction in the Scientific Literature. An Update on Their Morphology, Distribution, and Potential Roles in the Gut.International journal of molecular sciences · 2020Review
- Simulation and Modeling of Telocytes Behavior in Signaling and Intercellular Communication Processes.International journal of molecular sciences · 2020Article
- Immunohistochemical biomarkers and distribution of telocytes in ApoECell biology international · 2019Article
- Expression of toll-like receptors and their regulatory roles in murine cardiac telocytes.Journal of cellular and molecular medicine · 2019Article
- Morphological changes of telocytes in camel efferent ductules in response to seasonal variations during the reproductive cycle.Scientific reports · 2019Article
- Cyclooxygenase-2 in Endometriosis.International journal of biological sciences · 2019Review
- Telocytes enhanced the proliferation, adhesion and motility of endometrial stromal cells as mediated by the ERK pathway in vitro.American journal of translational research · 2019Article
- Uterine EMG activity in the non-pregnant sow during estrous cycle.BMC veterinary research · 2018Article
- C-kit receptor immunopositive interstitial cells (Cajal-type) in the porcine reproductive tract.Acta veterinaria Scandinavica · 2017Article
- Cellular Evidence of Telocytes as Novel Interstitial Cells Within the Magnum of Chicken Oviduct.Cell transplantation · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cells of the female reproductive tract are subject to hormonal control via sex steroid genomic receptors expressed at nuclear level. We previously showed that interstitial Cajal-like cells (ICLC) of human myometrium expressed estrogen and progesterone receptors (ER/PR). Our aim, based on these results, was to see if ER and/or PR could be found also in tubal ICLC. Indeed, we present here immunohistochemical evidence that ICLC of human Fallopian tube (isthmic region) have such receptors. Stromal ICLC, as well as ICLC among smooth muscle layers, were identified in tissue sections by their morphological features (e.g. several very long, moniliform, prolongations of cell body) as well as by c-kit positivity, vital staining with methylene blue or silver impregnation. Additional evidence was provided by sequential staining for c-kit and for PR on the same cell, by 'sandwich method'. In vitro, the 4th passage cell cultures from Fallopian tube muscularis exhibiting ICLC morphology showed the presence of ER-alpha and/or PR-A by immunofluorescence. In conclusion, our data suggest that ICLC could function as steroid sensors, and might be implicated in Fallopian tube motility (via gap junctions or juxta- and/or paracrine mechanisms).
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