Evidence map›Paper›PMID 20061852›Full record

ReviewJournal of burn care & research : official publication of the American Burn Association

Molecular mediators of angiogenesis.

Areck A Ucuzian, Andrew A Gassman, Andrea T East, Howard P Greisler

Abstract readReview
In one paragraph

Review in Journal of burn care & research : official publication of the American Burn Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

199 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Areck A UcuzianDepartment of Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
Andrew A Gassman
Andrea T East
Howard P Greisler

Funding

GROWTH FACTOR MEDIATION OF HEALING OF VASCULAR GRAFTSR01HL041272 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI GREISLER, HOWARD P · 1988 to 2006
$2.0M
NHLBI NIH HHS R01 HL041272NHLBI NIH HHS R01-HL41272
6 · The paper itself

Abstract

Angiogenesis, or the formation of new blood vessels from the preexisting vasculature, is a key component in numerous physiologic and pathologic responses and has broad impact in many medical and surgical specialties. In this review, we discuss the key cellular steps that lead to the neovascularization of tissues and highlight the main molecular mechanisms and mediators in this process. We include discussions on proteolytic enzymes, cell-matrix interactions, and pertinent cell signaling pathways and end with a survey of the mechanisms that lead to the stabilization and maturation of neovasculatures.

Indexed as

Endothelium, VascularExtracellular MatrixHumansIntercellular Signaling Peptides and ProteinsMatrix MetalloproteinasesNeovascularization, PhysiologicSignal TransductionIntercellular Signaling Peptides and ProteinsMatrix Metalloproteinases

Identifiers

PMID20061852
PMCPMC2818794

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.