Evidence map›Paper›PMID 20060885›Full record

ReviewExperimental gerontology2010

Experimental approaches to the study of epigenomic dysregulation in ageing.

Reid F Thompson, Melissa J Fazzari, John M Greally

Abstract readReview
In one paragraph

Review in Experimental gerontology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Reid F ThompsonDepartment of Genetics and Center for Epigenomics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Melissa J Fazzari
John M Greally

Funding

Genomic analysis of mammalian imprinted lociR01HD044078 · NICHD · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI GREALLY, JOHN · 2005 to 2008
$1.2M
NICHD NIH HHS R01 HD044078
6 · The paper itself

Abstract

In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to ageing research.

Indexed as

AgingAmino Acid SequenceAnimalsDNA MethylationEpigenesis, GeneticHistonesHumansMolecular Sequence DataMutationHistones

Identifiers

PMID20060885
PMCPMC2838972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.