ReviewCurrent opinion in immunology2010
The innate immune response in leprosy.
Review in Current opinion in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Inflammatory Mediators of Leprosy Reactional Episodes and Dental Infections: A Systematic Review.Mediators of inflammation · 2015Pooled it
- Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.PLoS neglected tropical diseases · 2014Trial
- Increased frequency of CD4 and CD8 regulatory T cells in individuals under 15 years with multibacillary leprosy.PloS one · 2013Trial
- Leprosy.Nature reviews. Disease primers · 2024Review
- Acid Fast Positivity Rate and Associated Factors of Leprosy in a Tertiary Care Hospital of Northeastern Ethiopia: Its Implication for Evidence-Based Leprosy Prevention and Control.Health science reports · 2024Article
- Different profiles of chemokines, cytokines and cell growth factors in plasma samples from patients with leprosy, leprosy reactions and households contacts.Memorias do Instituto Oswaldo Cruz · 2024Article
- Macrophage Biology in Human Granulomatous Skin Inflammation.International journal of molecular sciences · 2023Review
- A Bibliometric Analysis of Leprosy during 2000-2021 from Web of Science Database.International journal of environmental research and public health · 2022Article
- Gene Expression Profile ofFrontiers in medicine · 2022Article
- Observational
- Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO.Journal of leukocyte biology · 2021Article
- In search of biomarkers for leprosy by unraveling the host immune response to Mycobacterium leprae.Immunological reviews · 2021Review
- Correlation of Plasma Level of Insulin-Like Growth Factor-1 (IGF-1) with Bacterial Index on Leprosy Patients in Bali.Annals of dermatology · 2020Article
- Article
- Household Contacts of Leprosy Patients in Endemic Areas Display a Specific Innate Immunity Profile.Frontiers in immunology · 2020Article
- Relationship Between sCD163 and mCD163 and Their Implication in the Detection and Typing of Leprosy.Clinical, cosmetic and investigational dermatology · 2020Article
- Factors Associated with Multibacillary Leprosy in a Priority Region for Disease Control in Northeastern Brazil: A Retrospective Observational Study.Journal of tropical medicine · 2019Article
- Inflammatory cytokines in leprosy reactions and periodontal diseases.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese.American journal of human genetics · 2018Article
- The safety of influenza vaccine in clinically cured leprosy patients in China.Human vaccines & immunotherapeutics · 2018Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Investigation into the innate immune response in leprosy has provided insight into immunoregulation in human infectious disease. Key advances include the role of pattern recognition receptors in recognizing pathogen-associated molecular patterns of Mycobacterium leprae, cytokine release by innate immune cells, macrophage and dendritic cell differentiation, as well as antimicrobial effector pathways. These insights provide targets for therapeutic intervention in modulating the course of leprosy and other chronic infectious diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.