Evidence map›Paper›PMID 20058196›Full record

ReviewStem cell reviews and reports2009

Building a framework for embryonic microenvironments and cancer stem cells.

Antonio Ruiz-Vela, Cristóbal Aguilar-Gallardo, Carlos Simón

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Cervical cancer stem cells.Cell proliferation · 2015
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. The cancer stem cell niche--there goes the neighborhood?International journal of cancer · 2011
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Antonio Ruiz-VelaValencia Node of the Spanish Stem Cell Bank, Prince Felipe Research Center (CIPF), 46012 Valencia, Spain.
Cristóbal Aguilar-Gallardo
Carlos Simón
Centro de Investigacion Principe Felipe · ESValencian Infertility Institute · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The putative existence of a cancer stem cell niche consisting of bi-directional stromal and stem cell secreting factors that trigger cancer stem cell growth and proliferation has been hypothesized in the nervous and hematopoietic systems. In light of this theory, it has been proposed that embryonic stem cell microenvironments, upon interactions with cancer stem cells, may reprogram cancer cells resulting in a substantial inhibition of tumor cell properties. Here, we discuss emerging data that support this novel concept of cancer inhibitory factors produced in the context of embryonic microenvironments as well as by embryonic stem cells (ESCs).

Indexed as

Cell DifferentiationAnimalsBiomarkersEmbryonic Stem CellsHumansNeoplasmsNeoplastic Stem CellsBiomarkers

Identifiers

PMID20058196
OpenAlexW1977422172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.