Evidence map›Paper›PMID 20058099›Full record

ArticleEndocrine pathology2010

A double pituitary adenoma presenting as a prolactin-secreting tumor with partial response to medical therapy. Case report.

Claire I Coiré, Harley S Smyth, Dominic Rosso, Eva Horvath, Kalman Kovacs

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Multiple Pituitary Adenomas: A Systematic Review.Frontiers in endocrinology · 2016
    Review
  9. Review
  10. Resistant prolactinoma: Is it monoclonal or polyclonal?Indian journal of endocrinology and metabolism · 2013
    Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Claire I CoiréDepartment of Laboratory Medicine, Trillium Health Centre, Mississauga, ON, Canada. ccoire@thc.on.ca
Harley S Smyth
Dominic Rosso
Eva Horvath
Kalman Kovacs
Trillium Health Centre · CASt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Double pituitary adenomas are difficult to recognize pre-operatively as only a single mass may be appreciated on imaging. We present herein a giant prolactin-secreting pituitary adenoma in a middle-aged man that had responded partially to dopamine agonist therapy. The excised specimen demonstrated a double adenoma. The prolactin-producing one displayed the expected morphological changes resulting from medical therapy, while the other, a gonadotroph adenoma, did not. The failure of tumor shrinkage can be attributed to the presence of a double adenoma, a previously unreported cause of failure of medical therapy in prolactinoma.

Indexed as

AdenomaAdultAntineoplastic AgentsBreast Neoplasms, MaleCabergolineCombined Modality TherapyErgolinesGonadotrophsHumansMaleMicroscopy, Electron, TransmissionNeoplasms, Multiple PrimaryNeoplasms, Second PrimaryNeurofibromatosis 1Neurosurgical ProceduresProlactinomaAntineoplastic AgentsCabergolineErgolines

Identifiers

PMID20058099
OpenAlexW1989989650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.