ArticleBriefings in bioinformatics2010
Online tools for understanding rat physiology.
Article in Briefings in bioinformatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Deciphering the Enigma of Calcific Aortic Valve Disease: The Pivotal Role of Animal Models in Unraveling Pathogenesis and Advancing Therapeutic Strategies.Biomedicines · 2025Review
- Rat Models of Breast Cancer.Advances in experimental medicine and biology · 2025Review
- 2022 updates to the Rat Genome Database: a Findable, Accessible, Interoperable, and Reusable (FAIR) resource.Genetics · 2023Article
- A modified heterotopic heart transplantation in the rat - as an important model in experimental regeneration and replacement of the failing organ.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2020Review
- Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway.Journal of cellular and molecular medicine · 2019Article
- Quantitative phenotype analysis to identify, validate and compare rat disease models.Database : the journal of biological databases and curation · 2019Article
- Species generalization and differences in Hedgehog pathway regulation of fungiform and circumvallate papilla taste function and somatosensation demonstrated with sonidegib.Scientific reports · 2018Article
- A Primer for the Rat Genome Database (RGD).Methods in molecular biology (Clifton, N.J.) · 2018Article
- Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database.Physiological genomics · 2016Article
- Cellular resolution functional imaging in behaving rats using voluntary head restraint.Neuron · 2013Article
- The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications.Journal of biomedical semantics · 2013Article
- PhenoMiner: quantitative phenotype curation at the rat genome database.Database : the journal of biological databases and curation · 2013Article
- Beyond knockout rats: new insights into finer genome manipulation in rats.Cell cycle (Georgetown, Tex.) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Rat models have been used to investigate physiological and pathophysiological mechanisms for decades. With the availability of the rat genome and other online resources, tools to identify rat models that mimic human disease are an important step in translational research. Despite the large number of papers published each year using rat models, integrating this information remains a problem. Resources for the rat genome are continuing to grow rapidly, while resources providing access to rat phenotype data are just emerging. An overview of rat models of disease, tools to characterize strain by phenotype and genotype, and steps being taken to integrate rat physiological data is presented in this article. Integrating functional and physiological data with the rat genome will build a solid research platform to facilitate innovative studies to unravel the mechanisms resulting in disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.