ArticleEnvironmental health perspectives2010
Individual characteristics associated with PBDE levels in U.S. human milk samples.
Article in Environmental health perspectives, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Endocrine Disrupting Chemicals in Human Milk: A Systematic Review of Concentrations and Potential Health Implications.Current environmental health reports · 2025Pooled it
- Has Regulatory Action Reduced Human Exposure to Flame Retardants?Environmental science & technology · 2023Pooled it
- Distribution of polybrominated diphenyl ethers in breast milk, cord blood and placentas: a systematic review.Environmental science and pollution research international · 2017Pooled it
- Persistent Organic Pollutants in Austrian Human Breast Milk Collected between 2013 and 2016.Journal of xenobiotics · 2024Article
- Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food.EFSA journal. European Food Safety Authority · 2024Article
- Article
- Organophosphorus Flame Retardants and Plasticizers in Breast Milk from the United States.Environmental science & technology letters · 2019Article
- A contemporary assessment of polybrominated diphenyl ethers (PBDE) in the ambient air and soil of Azerbaijan.Environmental science and pollution research international · 2018Article
- Environmental Chemicals in Breast Milk and Formula: Exposure and Risk Assessment Implications.Environmental health perspectives · 2018Review
- Prenatal exposure to organophosphates and associations with birthweight and gestational length.Environment international · 2018Article
- Association between persistent endocrine-disrupting chemicals (PBDEs, OH-PBDEs, PCBs, and PFASs) and biomarkers of inflammation and cellular aging during pregnancy and postpartum.Environment international · 2018Article
- Article
- Adipose Tissue as a Site of Toxin Accumulation.Comprehensive Physiology · 2017Review
- Prenatal Serum Concentrations of Brominated Flame Retardants and Autism Spectrum Disorder and Intellectual Disability in the Early Markers of Autism Study: A Population-Based Case-Control Study in California.Environmental health perspectives · 2017Article
- RNA Sequencing Reveals Age and Species Differences of Constitutive Androstane Receptor-Targeted Drug-Processing Genes in the Liver.Drug metabolism and disposition: the biological fate of chemicals · 2017Article
- Polybrominated Diphenyl Ethers in Human Milk and Serum from the U.S. EPA MAMA Study: Modeled Predictions of Infant Exposure and Considerations for Risk Assessment.Environmental health perspectives · 2017Article
- Developmental Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice.Journal of the Endocrine Society · 2017Article
- Predictors of urinary flame retardant concentration among pregnant women.Environment international · 2017Article
- Lactational Exposure to Polybrominated Diphenyl Ethers and Its Relation to Early Childhood Anthropometric Measurements.Environmental health perspectives · 2016Article
- Endocrine disruptors alter social behaviors and indirectly influence social hierarchies via changes in body weight.Environmental health : a global access science source · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundReported polybrominated diphenyl ether (PBDE) concentrations in human samples in the United States have been higher than in Europe and Asia. Little is known about factors that contribute to individual variability in body burden.
objectiveIn this large study we measured PBDE concentrations in human milk from the United States during 2004-2006. We assessed characteristics associated with concentrations in milk and change in milk concentration between 3 and 12 months postpartum.
methodsWe analyzed 303 milk samples obtained 3 months postpartum for PBDEs. A second sample was analyzed for 83 women still lactating 12 months postpartum. PBDE concentrations in milk and variability by individual characteristics such as age, parity, and prepregnancy body mass index (BMI) were evaluated using generalized linear models.
resultsPBDE congeners BDEs 28, 47, 99, 100, and 153 were detected in > 70% of samples. BDE-47 concentrations were the highest, ranging from below the limit of detection to 1,430 ng/g lipid, with a median of 28 ng/g lipid. Concentrations of most individual PBDE congeners and the sum of BDEs 28, 47, 99, 100, and 153 (SigmaPBDE) were lower among mothers > 34 years of age compared with those 25-29 years of age and higher among mothers with high compared with normal BMI, after adjustment for other covariates. Parity was not associated with PBDE concentration. The change in SigmaPBDE concentration in milk between 3 and 12 months postpartum was highly variable (median increase, 14%; interquartile range, -26% to 50%).
conclusionsPBDEs were detected in nearly all human milk samples, varying by maternal weight and age and over the course of breast-feeding.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.