ArticleNano letters2010
Two-stage capture employing active transport enables sensitive and fast biosensors.
Article in Nano letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Active spiralling of microtubules driven by kinesin motors.Scientific reports · 2025Article
- Micro-/nanoscale robotics for chemical and biological sensing.Lab on a chip · 2023Review
- Fluctuotaxis: Nanoscale directional motion away from regions of fluctuation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Exploiting Electrostatic Interaction for Highly Sensitive Detection of Tumor-Derived Extracellular Vesicles by an Electrokinetic Sensor.ACS applied materials & interfaces · 2021Article
- An automated in vitro motility assay for high-throughput studies of molecular motors.Lab on a chip · 2018Article
- Non-equilibrium assembly of microtubules: from molecules to autonomous chemical robots.Chemical Society reviews · 2017Review
- Sensing surface mechanical deformation using active probes driven by motor proteins.Nature communications · 2016Article
- Engineering myosins for long-range transport on actin filaments.Nature nanotechnology · 2014Article
- Magnetic capture from blood rescues molecular motor function in diagnostic nanodevices.Journal of nanobiotechnology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanoscale sensors enable the detection of analytes with improved signal-to-noise ratio but suffer from mass transport limitations. Molecular shuttles, assembled from, e.g., antibody-functionalized microtubules and kinesin motor proteins, can selectively capture analytes from solution and deliver the analytes to a sensor patch. This two-stage process can accelerate mass transport to nanoscale biosensors and facilitate the rapid detection of analytes. Here, the possible increase of the signal-to-noise ratio is calculated, and the optimal layout of a system which integrates active transport is determined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.