Evidence map›Paper›PMID 20054604›Full record

ReviewClinical and experimental nephrology2010

Systemic lupus erythematosus after thymectomy for myasthenia gravis: a case report and review of the literature.

Hyder A Omar, Mohammed A Alzahrani, Ali A A Al Bshabshe, Alhussain Assiri, Medhat Shalaby, Ahmad Dwedar, Saad Rezk Abdulwahed, Mahmoud Rezk-Abd-Elwahed Hussein

Erratum issuedAbstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Clinical and experimental nephrology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Risk of incident autoimmune diseases in patients with thymectomy.Annals of clinical and translational neurology · 2020
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hyder A OmarDepartment of Medicine, College of Medicine, King Khalid University, Asser Central Hospital, Abha, Kingdom of Saudi Arabia. [corrected]
Mohammed A Alzahrani
Ali A A Al Bshabshe
Alhussain Assiri
Medhat Shalaby
Ahmad Dwedar
Saad Rezk Abdulwahed
Mahmoud Rezk-Abd-Elwahed Hussein
Al-Azhar University · EGAssiut University · EGKing Khalid University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a case of systemic lupus erythematosus in a 13-year-old girl who developed the disease 3 years after thymectomy performed for the treatment of myasthenia gravis. The presenting symptoms were fever, generalized fatigability, bilateral loin pain, weight loss, arthralgia, hair loss, and recurrent painless mouth ulcers. Laboratory findings revealed proteinuria, hematuria, anemia, leucopenia, a high titer of antinuclear antibodies (ANA), anti-dsDNA, and decreased complement (C3 and C4) levels. There was minimal ascitis and pericardial effusion. Renal biopsy showed lupus nephritis class IV. The diagnosis of systemic lupus erythematosus was established based on the clinical and laboratory findings. The activity of systemic lupus erythematosus was controlled by pulsed treatment with methyl prednisolone followed by long-term oral glucocorticoid and immunosuppressive therapy. This study highlights the immune system derangement following thymectomy. It also examines the relevant literature.

Indexed as

AdolescentFemaleHumansImmunosuppressive AgentsLupus Erythematosus, SystemicMethylprednisoloneMyasthenia GravisThymectomyImmunosuppressive AgentsMethylprednisolone

Identifiers

PMID20054604
OpenAlexW1975432366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.