Evidence map›Paper›PMID 20054481›Full record

ArticleInternational journal of molecular sciences2009

Immune response among patients exposed to molds.

David A Edmondson, Christy S Barrios, Trevor L Brasel, David C Straus, Viswanath P Kurup, Jordan N Fink

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. The effects of exposures to mycotoxins on immunity in children: A systematic review.Current problems in pediatric and adolescent health care · 2019
    Pooled it
  2. Article
  3. The Myth of Mycotoxins and Mold Injury.Clinical reviews in allergy & immunology · 2019
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

David A EdmondsonAllergy/Immunology Department at Ear, Nose and Throat Associates of North Central Wisconsin, 2801 Westhill Dr., Wausau, WI 54401, USA. dedmondson@westernu.edu
Christy S Barrios
Trevor L Brasel
David C Straus
Viswanath P Kurup
Jordan N Fink
Medical College of Wisconsin · USLovelace Respiratory Research Institute · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrocyclic trichothecenes, mycotoxins produced by Stachybotrys chartarum, have been implicated in adverse reactions in individuals exposed to mold-contaminated environments. Cellular and humoral immune responses and the presence of trichothecenes were evaluated in patients with mold-related health complaints. Patients underwent history, physical examination, skin prick/puncture tests with mold extracts, immunological evaluations and their sera were analyzed for trichothecenes. T-cell proliferation, macrocyclic trichothecenes, and mold specific IgG and IgA levels were not significantly different than controls; however 70% of the patients had positive skin tests to molds. Thus, IgE mediated or other non-immune mechanisms could be the cause of their symptoms.

Indexed as

Environmental ExposureAdaptive ImmunityAdolescentAdultCase-Control StudiesCell ProliferationChildEnvironmental IllnessFemaleHumansImmunoglobulinsMaleMiddle AgedSkin TestsStachybotrysT-LymphocytesImmunoglobulinsTrichothecenesclinical symptomsimmune responsemoldsmycotoxins

Identifiers

PMID20054481
PMCPMC2802005
OpenAlexW2033653125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.