Evidence map›Paper›PMID 20054162›Full record

ArticleObesity facts2008

Postprandial triglyceride response in men: role of overweight, abdominal fat and nutrition.

Britta Hitze, Diana Rubin, Ulf Helwig, Jürgen Schrezenmeir, Anja Bosy-Westphal, Manfred J Müller

Abstract read
In one paragraph

Article in Obesity facts, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Britta HitzeInstitute of Human Nutrition and Food Science, Christian-Albrechts-University Kiel, Kiel, Germany.
Diana Rubin
Ulf Helwig
Jürgen Schrezenmeir
Anja Bosy-Westphal
Manfred J Müller

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study analyses i) the effect of overweight, waist circumference and dietary habits on postprandial (pp) triglyceride (TG) response and compares ii) pp TG response with fasting TG levels and iii) pp TG peak values with TG-AUC (area under curve) with respect to cardiometabolic risk assessment.

methodsIn 100 men (44-68 years) body composition (air-displacement plethysmography), dietary habits, cardiometabolic risk and pp lipid metabolism (standardised lipid load) were assessed. A pp TG peak value of 260 mg/dl was used as a cut-off to classify TG normal- and high-responders.

resultspp TG response had positive associations with BMI (r = 0.24; p < 0.05), fat mass (r = 0.28; p < 0.01), waist circumference (r = 0.33; p < 0.01), systolic blood pressure (r = 0.21; p < 0.05), fasting (r = 0.29; p < 0.01) and pp glucose (r = 0.40; p < 0.001), fasting (r = 0.38; p < 0.001) and pp insulin levels (r = 0.46; p < 0.001), and inverse associations with HDL-C (r = -0.43; p < 0.001) and intake of dietary fibre (r = -0.31; p < 0.05). Fasting TG levels had a greater contribution to the variance in 12 of 14 cardiometabolic risk factors compared to pp TG response. TG-AUC was highly correlated to cardiometabolic risk.

conclusionOverweight, abdominal fat and a low intake of dietary fibre were determinants of increased pp TG response. Contrary to findings in younger normal-weight men, fasting TG levels had a stronger association with cardio metabolic risk compared to pp TG response. This might be explained by differences in fat mass.

Indexed as

Nutrition AssessmentAbdominal FatAdultAgedArea Under CurveBody CompositionBody Mass IndexCardiovascular DiseasesDietary FiberHumansLipid MetabolismMaleMiddle AgedOverweightPostprandial PeriodRisk FactorsDietary FiberTriglycerides

Identifiers

PMID20054162
PMCPMC6444805

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.