Evidence map›Paper›PMID 20054007›Full record

ArticleNeurology2010

The 5-year direct medical cost of neonatal and childhood stroke in a population-based cohort.

M A Gardner, N K Hills, S Sidney, S C Johnston, H J Fullerton

Open access · bronzeAbstract read
In one paragraph

Article in Neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 97 citations in OpenAlex.

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  16. Risk Factors of Pediatric Arterial Ischemic Stroke; A Regional Survey.International journal of preventive medicine · 2018
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M A GardnerDepartment og Pediatrics, University of California, San Francisco, Department of Neurology, San Francisco, CA 94143-0114, USA.
N K Hills
S Sidney
S C Johnston
H J Fullerton
Kaiser Permanente · US

Funding

VIPS: Vascular Effects of Infection in Pediatric StrokeR01NS062820 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEVEBER, GABRIELLE ALINE, FULLERTON, HEATHER J · 2009 to 2013
$6.6M
20 YEAR CHANGES IN FITNESS &CARDIOVASCULAR DISEASE RISKR01HL078972 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 2005 to 2008
$6.1M
Disability and Health Outcomes in COPDR01HL077618 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLANC, PAUL D · 2004 to 2008
$3.3M
Accuracy of Physical Activity Measures in Cancer StudiesR01CA103974 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI STERNFELD, BARBARA · 2005 to 2009
$2.4M
Validation of the NIH Stroke Scale in ChildrenR01NS050488 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ICHORD, REBECCA N · 2006 to 2008
$1.1M
The Role of Infection in Childhood StrokeK02NS053883 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FULLERTON, HEATHER J · 2006 to 2010
$831k
Acute Outcomes &Management of TIA with Carotid DiseaseK23NS049230 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NGUYEN-HUYNH, MAI N · 2005 to 2009
$807k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
NCI NIH HHS R01 CA103974NHLBI NIH HHS N01 HC-48050NHLBI NIH HHS R01 HL077618NHLBI NIH HHS R01 HL078972NINDS NIH HHS K02 NS053883NINDS NIH HHS K02NS053883NINDS NIH HHS K23 NS049230NINDS NIH HHS R01 NS050488NINDS NIH HHS R01 NS062820
6 · The paper itself

Abstract

backgroundDespite increasing awareness of the long-term impact of pediatric stroke, there are few estimates of the costs of care. We examined acute and 5-year direct costs of neonatal and childhood stroke in a population-based cohort in Northern California.

methodsWe obtained electronic cost data for 266 children with neurologist-confirmed strokes, and 786 age-matched stroke-free controls, within the population of all children (<20 years) enrolled in a large managed care plan from 1996 through 2003. Cost data included all inpatient and outpatient health service costs including care at out-of-plan facilities. Costs were assessed for 5 years after stroke, expressed in 2003 US dollars, and stratified by age at stroke onset (neonatal, defined as <29 days of life, vs childhood). Stroke costs were adjusted for costs in stroke-free age-matched controls.

resultsAverage adjusted 5-year costs for pediatric stroke are substantial: $51,719 for neonatal stroke and $135,161 for childhood stroke. The average cost of a childhood stroke admission was $81,869. The average birth admission cost for a neonatal stroke was $39,613; adjustment for control birth admission costs reduced this by only $4,792, suggesting the stroke accounted for 88% of costs. Even among neonates whose strokes were not recognized until later in childhood ("presumed perinatal strokes"), admission costs exceeded those of controls. Chronic costs were highest in the first year poststroke, but continued to exceed control costs even in the fifth year by an average of $2,016.

conclusionsThe economic burden of neonatal and childhood stroke is both large and sustained.

Indexed as

CaliforniaCase-Control StudiesChildChild, PreschoolCohort StudiesCommunity Health PlanningCosts and Cost AnalysisFemaleHealth Care CostsHumansInfantInfant, NewbornInsurance Claim ReviewMaleNeeds AssessmentOutcome Assessment, Health Care

Identifiers

PMID20054007
PMCPMC2816005
OpenAlexW2041726006

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.