Evidence map›Paper›PMID 20053522›Full record

ArticleAlcohol (Fayetteville, N.Y.)

Validity of the T-ACE in pregnancy in predicting child outcome and risk drinking.

Lisa M Chiodo, Robert J Sokol, Virginia Delaney-Black, James Janisse, John H Hannigan

Abstract readValidation Study
In one paragraph

Article in Alcohol (Fayetteville, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Screening for Alcohol Use in Pregnancy: a Review of Current Practices and Perspectives.International journal of mental health and addiction · 2023
    Article
  4. Prenatal alcohol use as a risk for attention-deficit/hyperactivity disorder.European archives of psychiatry and clinical neuroscience · 2019
    Article
  5. Prenatal Alcohol Screening During Pregnancy by Midwives and Nurses.Alcoholism, clinical and experimental research · 2019
    Article
  6. Article
  7. Fetal alcohol-spectrum disorders: identifying at-risk mothers.International journal of women's health · 2016
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fetal alcohol spectrum disorders: from research to policy.Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa M ChiodoCollege of Nursing, Wayne State University, Detroit, MI 48202, USA. lchiodo@med.wayne.edu
Robert J Sokol
Virginia Delaney-Black
James Janisse
John H Hannigan

Funding

PREG WOMEN/FETUSES AT RISK FOR ALC BIRTH DEFECTSN01AA083019 · NIAAA · WAYNE STATE UNIVERSITY · PI HANNIGAN, JOHN H · 1998 to 2000
$149k
PRENATAL COCAINE/ALCOHOL EXPOSURE--AGE OUTCOMESR01DA008524 · NIDA · WAYNE STATE UNIVERSITY · PI DELANEY-BLACK, VIRGINIA · 1994 to 1998
–
NIAAA NIH HHS N01 AA083019NIAAA NIH HHS N01-AA83019NIDA NIH HHS R01 DA008524NIDA NIH HHS R01-DA08524
6 · The paper itself

Abstract

Preventing fetal alcohol spectrum disorders (FASDs) requires detection of in-pregnancy maternal risk drinking. The widely used T-ACE screen has been applied in various ways, although the impact of those different uses on effectiveness is uncertain. We examined relations among different T-ACE scoring criteria, maternal drinking, and child outcome. Self-reported across-pregnancy maternal drinking was assessed in 75 African-American women. The different T-ACE criteria used varied the level of drinking that defined tolerance (two or three drinks) and the total T-ACE score cut-points (two or three). Receiver operator curves and regression analysis assessed the significance of relations. Increasing the total T-ACE score cut-point to 3 almost doubled specificity in detecting risk drinking whereas maintaining adequate sensitivity, equivalent to that in the original report, and identified substantially more neurobehavioral deficits in children. Redefining tolerance at three drinks did not improve T-ACE effectiveness in predicting outcomes. This study is among the first to show the ability of an in-pregnancy T-ACE assessment to predict child neurodevelopmental outcome. In addition, increasing the total T-ACE score criterion (from 2 to 3) improved identification of non-drinking mothers and unaffected children with little loss in detection of drinkers and affected children. Efficient in-pregnancy screens for risk drinking afford greater opportunities for intervention that could prevent/limit FASDs.

Indexed as

Pregnancy OutcomeAdultAlcohol DrinkingAlcoholismBlack or African AmericanCentral Nervous System DiseasesChild, PreschoolDrug ToleranceFemaleFetal Alcohol Spectrum DisordersHumansMaleMass ScreeningMental DisordersPregnancyPrenatal Exposure Delayed Effects

Identifiers

PMID20053522
PMCPMC2891940

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.