ArticleInternational urogynecology journal2010
Polypropylene as a reinforcement in pelvic surgery is not inert: comparative analysis of 100 explants.
Article in International urogynecology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- Detection of biofilms on explanted urinary incontinence slings and their relationship with pain, exposure, or urinary tract complications.Applied and environmental microbiology · 2026Article
- Distinct microbiome profiles on vaginally inserted polypropylene midurethral mesh slings compared to vaginal, urinary, and skin microbiomes.Applied and environmental microbiology · 2025Article
- Platelet-Rich Therapies in Hernia Repair: A Comprehensive Review of the Impact of Platelet Concentrates on Mesh Integration in Hernia Management.Biomolecules · 2024Review
- Characterization in respect to degradation of titanium-coated polypropylene surgical mesh explanted from humans.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Polypropylene Pelvic Mesh: What Went Wrong and What Will Be of the Future?Biomedicines · 2023Review
- Analyzing material changes consistent with degradation of explanted polymeric hernia mesh related to clinical characteristics.Surgical endoscopy · 2022Article
- Development of 3D Printed Biodegradable Mesh with Antimicrobial Properties for Pelvic Organ Prolapse.Polymers · 2022Article
- Host-biomaterial interactions in mesh complications after pelvic floor reconstructive surgery.Nature reviews. Urology · 2021Review
- A novel characterisation approach to reveal the mechano-chemical effects of oxidation and dynamic distension on polypropylene surgical mesh.RSC advances · 2021Article
- Anti-inflammatory coating of hernia repair meshes: a 5-rabbit study.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Effect of the platelet-rich plasma covering of polypropylene mesh on oxidative stress, inflammation, and adhesions.International urogynecology journal · 2020Article
- Complications related to use of mesh implants in surgical treatment of stress urinary incontinence and pelvic organ prolapse: infection or inflammation?World journal of urology · 2020Review
- Long-Lasting Examinations of Surface and Structural Properties of Medical Polypropylene Modified with Silver Nanoparticles.Polymers · 2019Article
- Abnormal vaginal microbiome associated with vaginal mesh complications.Neurourology and urodynamics · 2019Article
- Polypropylene mesh and systemic side effects in inguinal hernia repair: current evidence.Irish journal of medical science · 2019Review
- Antibacterial Properties of Mussel-Inspired Polydopamine Coatings Prepared by a Simple Two-Step Shaking-Assisted Method.Frontiers in chemistry · 2019Article
- Hernia repair with polypropylene mesh is not associated with an increased risk of autoimmune disease in adult men.Hernia : the journal of hernias and abdominal wall surgery · 2017Article
- The myth: in vivo degradation of polypropylene-based meshes.International urogynecology journal · 2017Article
- Reply to "In vivo polypropylene mesh degradation is hardly a myth".International urogynecology journal · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisCurrently, most implants used for reinforcement in surgical treatment of pelvic floor disorders are knitted monofilament polypropylene (PP). While previously recognized as inert, PP is associated with high complication rates. Some recent literature suggests polyester prosthetics based on poly(ethylene terephthalate) (PET), which may be more inert in vivo.
methodsA sample of 100 implants explanted from patients due to complications was examined to evaluate the relative degradation characteristics of PP and PET prosthetics. Histological, microscopic (scanning electron microscopy, SEM) and chemical analysis (Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC)) were conducted on these explants.
resultsPoly(ethylene terephtahlate) explants appeared to sustain less degradation in vivo than the PP explants observed in this cohort.
conclusionsThis is the first study to evaluate synthetic implants used in a vaginal approach for pelvic floor reinforcement. The study provides evidence contrary to published literature characterizing PP as inert in such applications. Additionally, the study suggests the need for clinical trials comparatively investigating the performance of new types of monofilament prosthetics, such as those comprising PET.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.