Evidence map›Paper›PMID 20052559›Full record

SynthesisJournal of cancer survivorship : research and practice2010

An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis.

Rebecca M Speck, Kerry S Courneya, Louise C Mâsse, Sue Duval, Kathryn H Schmitz

Erratum issued 9 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 9 registered trials, which are not on this map. Cited by 584 papers, 25 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
584citing papers in PubMed, 25 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01515124 nacompletednot on this mapstarted 2012, after this paper: background citation

The Women In Steady Exercise Research (WISER) Survivor Trial & Cost of Illness and Cost Effectiveness of Alternative Management Strategies

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2012 to 2016Enrolled450ConditionsLymphedemaArmsExercise Intervention, Weight Loss Intervention
NCT01843608 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Effect of Combined Training Post-treatment Intervention in Lean Body Mass Recovery in Breast Cancer Survival. A Randomised Controlled Trial.

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2013 to 2014Enrolled90ConditionsSarcopenic Obesity in Breast Cancer Survival, Muscle Strength Quantitative Trait Locus 1, Cardiopulmonary Capacity, Quality of LifeArmsPhysical Intervention
NCT03475433 completednot on this mapstarted 2018, after this paper: background citation

An Observational Prospective Cohort Study About Quality of Life in Relation to the Physical Activity of Taiwanese Breast and Prostate Cancer Patients.

TypeobservationalSponsorTaipei Medical UniversityRan2018 to 2018Enrolled40ConditionsNeoplasm of Breast (Disorder), Carcinoma of Prostate (Disorder)ArmsActigraphy device
NCT03524755 nacompletednot on this mapstarted 2013, after this paper: background citation

Effects of a Progressive Resistance Training in Cachectic Cancer Patients During Radiotherapy - a Randomized Controlled Pilot Trial

TypeinterventionalSponsorLudwig-Maximilians - University of MunichRan2013 to 2015Enrolled20ConditionsHead and Neck Cancer, Cachexia, Cancer, Resistance TrainingArmsExercise
NCT03649737 nacompletednot on this mapstarted 2018, after this paper: background citation

Pilot Study of a Progressive Exercise Program Among Lung Cancer Patient-Partner Dyads

TypeinterventionalSponsorOHSU Knight Cancer InstituteRan2018 to 2019Enrolled46ConditionsLung Cancer, Depression, Physical Activity, Quality of LifeArmsExercise Intervention, Survey Administration, Quality-of-Life Assessment
NCT03860740 completednot on this mapstarted 2016, after this paper: background citation

Effect of Physical Exercise on Ki-67 Levels in Women With Operable Breast Cancer Hormonal Receptor Positive, HER2 Negative

TypeobservationalSponsorSpanish Breast Cancer Research GroupRan2016 to 2021Enrolled12ConditionsBreast Cancer, Luminal BArmsExercise, Stretching
NCT04316962 nacompletednot on this mapstarted 2016, after this paper: background citation

Cancer Rehabilitation in Primary Health Care

TypeinterventionalSponsorUniversity of BergenRan2016 to 2022Enrolled72ConditionsCancer Survivors, All CancersArmsComplex cancer rehabilitation
NCT05349227 narecruitingnot on this mapstarted 2022, after this paper: background citation

Comprehensive Outcomes for After Cancer Health (COACH): the Feasibility and Impact of an MHealth Augmented Coaching Program for Self-Management in Cancer Survivors

TypeinterventionalSponsorPack HealthRan2022 to 2027Enrolled625ConditionsOvarian Cancer, Breast Cancer, Lung Cancer, Gastric CancerArmsDigital Health Coaching Program, Fitbit
NCT05931874 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Fit2ThriveMIND: Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors

TypeinterventionalSponsorNorthwestern UniversityRan2024 to 2027Enrolled304ConditionsBreast CancerArmsCore Intervention, E-Coach, Buddy, General Mindfulness Training, MVPA-Specific Mindfulness Training
3 · Its place in the literature

Who cites it

584 citing papers in PubMed, 25 syntheses or guidelines pooled it.

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  17. Exercise Therapy and Radiation Therapy for Cancer: A Systematic Review.International journal of radiation oncology, biology, physics · 2021
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524 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

5 authors.

Rebecca M SpeckDivision of Clinical Epidemiology, University of Pennsylvania, Philadelphia, PA, USA.
Kerry S Courneya
Louise C Mâsse
Sue Duval
Kathryn H Schmitz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionApproximately 11.1 million cancer survivors are alive in the United States. Activity prescriptions for cancer survivors rely on evidence as to whether exercise during or after treatment results in improved health outcomes. This systematic review and meta-analysis evaluates the extent to which physical activity during and post treatment is appropriate and effective across the cancer control continuum.

methodsA systematic quantitative review of the English language scientific literature searched controlled trials of physical activity interventions in cancer survivors during and post treatment. Data from 82 studies were abstracted, weighted mean effect sizes (WMES) were calculated from 66 high quality studies, and a systematic level of evidence criteria was applied to evaluate 60 outcomes. Reports of adverse events were abstracted from all studies.

resultsQuantitative evidence shows a large effect of physical activity interventions post treatment on upper and lower body strength (WMES = 0.99 & 0.90, p < 0.0001 & 0.024, respectively) and moderate effects on fatigue and breast cancer-specific concerns (WMES = -0.54 & 0.62, p = 0.003 & 0.003, respectively). A small to moderate positive effect of physical activity during treatment was seen for physical activity level, aerobic fitness, muscular strength, functional quality of life, anxiety, and self-esteem. With few exceptions, exercise was well tolerated during and post treatment without adverse events.

conclusionsCurrent evidence suggests many health benefits from physical activity during and post cancer treatments. Additional studies are needed in cancer diagnoses other than breast and with a focus on survivors in greatest need of improvements for the health outcomes of interest.

Indexed as

ExerciseClinical Trials as TopicHumansNeoplasmsSurvivors

Identifiers

PMID20052559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.