ArticleEuropean journal of human genetics : EJHG2010
Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages.
Article in European journal of human genetics : EJHG, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- A comprehensive analysis of Y-chromosomal diversity in Colombian populations.International journal of legal medicine · 2026Article
- Impact of patrilocality on contrasting patterns of paternal and maternal heritage in Central-West Africa.Scientific reports · 2024Article
- Population genetic study of 17 Y-STR Loci of the Sorani Kurds in the Province of Sulaymaniyah, Iraq.BMC genomics · 2022Article
- The COVID-19 Pandemic and Explaining Outcomes in Africa: Could Genomic Variation Add to the Debate?Omics : a journal of integrative biology · 2022Review
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- Searching for the roots of the first free African American community.Scientific reports · 2020Article
- Y Haplogroup Diversity of the Dominican Republic: Reconstructing the Effect of the European Colonization and the Trans-Atlantic Slave Trades.Genome biology and evolution · 2020Article
- Y-chromosome and Surname Analyses for Reconstructing Past Population Structures: The Sardinian Population as a Test Case.International journal of molecular sciences · 2019Article
- Genetic history of Chad.American journal of physical anthropology · 2018Article
- The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages.Genome biology · 2018Article
- Patterns of passage into protected areas: Drivers and outcomes of Fulani immigration, settlement and integration into the Kachia Grazing Reserve, northwest Nigeria.Pastoralism : research, policy and practice · 2018Article
- The study of human Y chromosome variation through ancient DNA.Human genetics · 2017Review
- Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations.American journal of human genetics · 2016Article
- Detection of phylogenetically informative polymorphisms in the entire euchromatic portion of human Y chromosome from a Sardinian sample.BMC research notes · 2015Article
- Genome-wide ancestry of 17th-century enslaved Africans from the Caribbean.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia.European journal of human genetics : EJHG · 2015Article
- Genetic Diversity in the Lesser Antilles and Its Implications for the Settlement of the Caribbean Basin.PloS one · 2015Article
- Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route.PloS one · 2015Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Although human Y chromosomes belonging to haplogroup R1b are quite rare in Africa, being found mainly in Asia and Europe, a group of chromosomes within the paragroup R-P25(*) are found concentrated in the central-western part of the African continent, where they can be detected at frequencies as high as 95%. Phylogenetic evidence and coalescence time estimates suggest that R-P25(*) chromosomes (or their phylogenetic ancestor) may have been carried to Africa by an Asia-to-Africa back migration in prehistoric times. Here, we describe six new mutations that define the relationships among the African R-P25(*) Y chromosomes and between these African chromosomes and earlier reported R-P25 Eurasian sub-lineages. The incorporation of these new mutations into a phylogeny of the R1b haplogroup led to the identification of a new clade (R1b1a or R-V88) encompassing all the African R-P25(*) and about half of the few European/west Asian R-P25(*) chromosomes. A worldwide phylogeographic analysis of the R1b haplogroup provided strong support to the Asia-to-Africa back-migration hypothesis. The analysis of the distribution of the R-V88 haplogroup in >1800 males from 69 African populations revealed a striking genetic contiguity between the Chadic-speaking peoples from the central Sahel and several other Afroasiatic-speaking groups from North Africa. The R-V88 coalescence time was estimated at 9.2-5.6 [corrected] kya, in the early mid Holocene. We suggest that R-V88 is a paternal genetic record of the proposed mid-Holocene migration of proto-Chadic Afroasiatic speakers through the Central Sahara into the Lake Chad Basin, and geomorphological evidence is consistent with this view.
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