ReviewCurrent opinion in nephrology and hypertension2010
Health-related quality of life outcomes in chronic kidney disease.
Review in Current opinion in nephrology and hypertension, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- Health related quality of life utility weights for economic evaluation through different stages of chronic kidney disease: a systematic literature review.Health and quality of life outcomes · 2020Pooled it
- Patient-Centred Outcomes in Anaemia and Renal Disease: A Systematic Review.Kidney diseases (Basel, Switzerland) · 2020Pooled it
- Prevalence of chronic kidney disease in South Asia: a systematic review.BMC nephrology · 2018Pooled it
- Chronic kidney disease and support provided by home care services: a systematic review.BMC nephrology · 2014Pooled it
- Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease.PloS one · 2016Trial
- Pharmacist intervention in improving hypertension-related knowledge, treatment medication adherence and health-related quality of life: a non-clinical randomized controlled trial.Health expectations : an international journal of public participation in health care and health policy · 2015Trial
- The effect of lowering salt intake on ambulatory blood pressure to reduce cardiovascular risk in chronic kidney disease (LowSALT CKD study): protocol of a randomized trial.BMC nephrology · 2012Trial
- The association of moderate renal dysfunction with impaired preference-based health-related quality of life: third Korean national health and nutritional examination survey.BMC nephrology · 2012Trial
- Socio-demographic characteristics associated with SF-6D v2 utility scores in patients undergoing dialysis in China: contributions of the quantile regression.Health and quality of life outcomes · 2025Article
- Exploring factors associated with Kidney Disease Quality of Life in patients with advanced chronic kidney disease: the Reach-J CKD cohort study.Clinical and experimental nephrology · 2025Article
- Influence of Frailty on Health-Related Quality of Life Trajectories in Chronic Kidney Disease Patients in India.Journal of clinical medicine · 2025Article
- Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD.Kidney international reports · 2024Review
- Investigating the relationship between FRailty And Quality of LIfe in patients with heart faiLure and CKD (FRAIL study).ESC heart failure · 2024Article
- Looking into the Eyes to See the Heart of Chronic Kidney Disease Patients.Life (Basel, Switzerland) · 2024Article
- Comprehensive geriatric assessment of older patients with renal disease: a cross-sectional survey.Scientific reports · 2024Article
- Effect of Executive Function on Health-Related Quality of Life in Children with Chronic Kidney Disease.International journal of nephrology and renovascular disease · 2024Article
- Observational
- High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Article
- [Quality of life in patients with renal replacement therapy in hemodialysis].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
- A multicenter descriptive analysis of anemia management in hemodialysis patients and its association with quality of life.BMC nephrology · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewPatients with chronic kidney disease (CKD) endure compromised health-related quality of life (HRQOL). Although the link between HRQOL and increased mortality in patients with end-stage renal disease (ESRD) is well documented, less is known about the relationship between CKD and HRQOL. This article reviews the recent evidence on HRQOL, its correlates and proposed intervention strategies to improve HRQOL in CKD. RECENT
findingsA growing body of literature indicates that various comorbid conditions related to CKD play a substantial role in impaired HRQOL in CKD. Hypertension, both a cause and complication of CKD, negatively affects HRQOL due to associated comorbidities, side effects from antihypertensive medications and awareness of the diagnosis. Anemia has been associated with HRQOL, but concerns about the safety of erythropoietin-stimulating agents (ESAs) have led to more conservative anemia treatment. Frailty, symptom burden and depression are also major contributory factors to HRQOL in CKD. SUMMARY: Certain determinants of HRQOL in CKD, namely anemia and depression, are treatable. Early identification and correction may improve overall well being of patients. Clinical trials are required to demonstrate whether treatment interventions benefit HRQOL in this high-risk population. Furthermore, whether integration of HRQOL assessment into routine clinical practice will improve HRQOL outcomes remains to be determined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.