Evidence map›Paper›PMID 20051368›Full record

ReviewCancer prevention research (Philadelphia, Pa.)2010

One-hit effects and cancer.

Maria D Iniesta, Janet Chien, Max Wicha, Sofia D Merajver

Abstract readCommentReview
PubMed Publisher
In one paragraph

Review in Cancer prevention research (Philadelphia, Pa.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria D IniestaDepartment of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, 48109, USA.
Janet Chien
Max Wicha
Sofia D Merajver
University of Michigan–Ann Arbor · US

Funding

PREVENTION OF MAMMARY CANCER IN HER-2NEU TRANSGENIC MICER01CA077612 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MERAJVER, SOFIA DIANA · 1999 to 2007
$2.2M
NCI NIH HHS R01-CA77612
6 · The paper itself

Abstract

This perspective on Bellacosa et al. (beginning on p. 48 in this issue of the journal) discusses the important biology of microscopically normal tissues in carriers of germ-line BRCA1 or BRCA2 mutations. The work of Bellacosa et al. is an important step toward discerning which pathways may be altered when one BRCA allele is inactivated.

Indexed as

Genes, BRCA1Genes, BRCA2Breast NeoplasmsFemaleGenetic Predisposition to DiseaseGerm-Line MutationHumansOvarian Neoplasms

Identifiers

PMID20051368
OpenAlexW2017376554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.