Evidence map›Paper›PMID 20051144›Full record

ArticleBMC genetics2010

A comparison of SNP and STR loci for delineating population structure and performing individual genetic assignment.

Kevin A Glover, Michael M Hansen, Sigbjørn Lien, Thomas D Als, Bjørn Høyheim, Oystein Skaala

Open access · diamondAbstract readComparative Study
In one paragraph

Article in BMC genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 148 citations in OpenAlex.

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  11. SNPs in Sheep: Characterization of Lithuanian Sheep Populations.Animals : an open access journal from MDPI · 2021
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  19. Ancestry-informative marker (AIM) SNP panel for the Malay population.International journal of legal medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Kevin A GloverInstitute of Marine Research, PO Box 1870, Nordnes N- 5817 Bergen, Norway. kevin.glover@imr.no
Michael M Hansen
Sigbjørn Lien
Thomas D Als
Bjørn Høyheim
Oystein Skaala
Norwegian Institute of Marine Research · NONorwegian University of Life Sciences · NOAarhus University · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTechnological advances have lead to the rapid increase in availability of single nucleotide polymorphisms (SNPs) in a range of organisms, and there is a general optimism that SNPs will become the marker of choice for a range of evolutionary applications. Here, comparisons between 300 polymorphic SNPs and 14 short tandem repeats (STRs) were conducted on a data set consisting of approximately 500 Atlantic salmon arranged in 10 samples/populations.

resultsGlobal FST ranged from 0.033-0.115 and -0.002-0.316 for the 14 STR and 300 SNP loci respectively. Global FST was similar among 28 linkage groups when averaging data from mapped SNPs. With the exception of selecting a panel of SNPs taking the locus displaying the highest global FST for each of the 28 linkage groups, which inflated estimation of genetic differentiation among the samples, inferred genetic relationships were highly similar between SNP and STR data sets and variants thereof. The best 15 SNPs (30 alleles) gave a similar level of self-assignment to the best 4 STR loci (83 alleles), however, addition of further STR loci did not lead to a notable increase assignment whereas addition of up to 100 SNP loci increased assignment.

conclusionWhilst the optimal combinations of SNPs identified in this study are linked to the samples from which they were selected, this study demonstrates that identification of highly informative SNP loci from larger panels will provide researchers with a powerful approach to delineate genetic relationships at the individual and population levels.

Indexed as

Genetics, PopulationMicrosatellite RepeatsPolymorphism, Single NucleotideAnimalsAquacultureGenetic LociGenotypeNorwaySalmon

Identifiers

PMID20051144
PMCPMC2818610
OpenAlexW2128195336

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.