ArticleBMC genomics2010
An evolutionary consequence of dosage compensation on Drosophila melanogaster female X-chromatin structure?
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Induction and inhibition of Drosophila X chromosome gene expression are both impeded by the dosage compensation complex.G3 (Bethesda, Md.) · 2022Article
- The evolution of sex-biased gene expression in theGenome research · 2020Article
- Article
- Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains.Epigenetics & chromatin · 2018Article
- Dosage Compensation and the Distribution of Sex-Biased Gene Expression in Drosophila: Considerations and Genomic Constraints.Journal of molecular evolution · 2016Article
- An H4K16 histone acetyltransferase mediates decondensation of the X chromosome inEpigenetics & chromatin · 2016Article
- High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.Molecular cell · 2015Article
- Dosage compensation in Drosophila.Cold Spring Harbor perspectives in biology · 2015Review
- X Chromosome and Autosome Dosage Responses in Drosophila melanogaster Heads.G3 (Bethesda, Md.) · 2015Article
- The chromatin landscape of Drosophila: comparisons between species, sexes, and chromosomes.Genome research · 2014Article
- Transcriptional control of a whole chromosome: emerging models for dosage compensation.Nature structural & molecular biology · 2014Review
- Differential effect of aneuploidy on the X chromosome and genes with sex-biased expression in Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Codon usage bias and effective population sizes on the X chromosome versus the autosomes in Drosophila melanogaster.Molecular biology and evolution · 2013Article
- The genomic distribution of sex-biased genes in drosophila serrata: X chromosome demasculinization, feminization, and hyperexpression in both sexes.Genome biology and evolution · 2013Article
- POF regulates the expression of genes on the fourth chromosome in Drosophila melanogaster by binding to nascent RNA.Molecular and cellular biology · 2012Article
- Faster-X evolution of gene expression in Drosophila.PLoS genetics · 2012Article
- Global analysis of the relationship between JIL-1 kinase and transcription.PLoS genetics · 2011Article
- Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-seq.PLoS biology · 2011Article
- Gene duplication and the genome distribution of sex-biased genes.International journal of evolutionary biology · 2011Article
- Hyperexpression of the X chromosome in both sexes results in extensive female bias of X-linked genes in the flour beetle.Genome biology and evolution · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundX chromosomes are subject to dosage compensation in Drosophila males. Dosage compensation requires cis sequence features of the X chromosome that are present in both sexes by definition and trans acting factors that target chromatin modifying machinery to the X specifically in males. The evolution of this system could result in neutral X chromatin changes that will be apparent in females.
resultsWe find that the general chromatin structure of female X chromosomes is distinct from autosomes. Additionally, specific histone marks associated with dosage compensation and active chromatin marks on the male X chromosome are also enriched on the X chromosomes of females, albeit to a lesser degree.
conclusionsOur data indicate that X chromatin structure is fundamentally different from autosome structure in both sexes. We suggest that the differences between the X chromosomes and autosomes in females are a consequence of mechanisms that have evolved to ensure sufficient X chromosome expression in the soma of males.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.