Words of wisdom. Re: Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. Shai I, Schwarzfuchs D, Henkin Y, Shahar DR, Witkow S, Greenberg I, Golan R, Fraser D, Bolotin A, Vardi H, Tangi-Rozental O, Zuk-Ramot R, Sarusi B, Brickner D, Schwartz Z, Sheiner E, Marko R, Katorza E, Thiery J, Fiedler GM, Blüher M, Stumvoll M, Stampfer MJ. Dietary Intervention Randomized Controlled Trial (DIRECT) Group. N Engl J Med 2008;359:229-41.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Obesity treatment by very low-calorie-ketogenic diet at two years: reduction in visceral fat and on the burden of disease.Endocrine · 2016
   Trial
2. Human experience with an endoluminal, endoscopic, gastrojejunal bypass sleeve.Surgical endoscopy · 2011
   Trial
3. Multidisciplinary Progress in Obesity Research.Genes · 2022
   Review
4. Ketogenic diet in the treatment of cancer - Where do we stand?Molecular metabolism · 2020
   Review
5. Treatment of non-alcoholic fatty liver disease - Current perspectives.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
   Review
6. Lessons Learned from the POUNDS Lost Study: Genetic, Metabolic, and Behavioral Factors Affecting Changes in Body Weight, Body Composition, and Cardiometabolic Risk.Current obesity reports · 2019
   Review
7. Fad Diets: Hype or Hope?Current nutrition reports · 2018
   Review
8. The Mediterranean Diet: Lost in Translation.Current hypertension reports · 2018
   Review
9. Preventing Type 2 Diabetes with Home Cooking: Current Evidence and Future Potential.Current diabetes reports · 2018
   Review
10. Comprehensive Cardiovascular Risk Reduction and Cardiac Rehabilitation in Diabetes and the Metabolic Syndrome.The Canadian journal of cardiology · 2016
    Review
11. Vaspin in obesity and diabetes: pathophysiological and clinical significance.Endocrine · 2012
    Review
12. Successful weight loss and maintenance in everyday clinical practice with an individually tailored change of eating habits on the basis of food energy density.European journal of nutrition · 2011
    Article

Corrections and comments

• Comment on
  Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet.2008

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.