ReviewPediatric nephrology (Berlin, Germany)2010
Molecular anatomy of the kidney: what have we learned from gene expression and functional genomics?
Review in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics.Developmental cell · 2024Article
- Developmental Programming of Renal Function and Re-Programming Approaches.Frontiers in pediatrics · 2018Review
- A brief review of kidney development, maturation, developmental abnormalities, and drug toxicity: juvenile animal relevancy.Journal of toxicologic pathology · 2017Review
- Each niche has an actor: multiple stem cell niches in the preterm kidney.Italian journal of pediatrics · 2015Review
- PAX2 polymorphisms and congenital abnormalities of the kidney and urinary tract in a Brazilian pediatric population: evidence for a role in vesicoureteral reflux.Molecular diagnosis & therapy · 2014Article
- Stromal cells in tissue homeostasis: balancing regeneration and fibrosis.Nature reviews. Nephrology · 2013Review
- Ion channels in renal disease.Chemical reviews · 2012Review
- Early risk factors for neonatal mortality in CAKUT: analysis of 524 affected newborns.Pediatric nephrology (Berlin, Germany) · 2012Article
- Clinical course of 822 children with prenatally detected nephrouropathies.Clinical journal of the American Society of Nephrology : CJASN · 2012Article
- The GUDMAP database--an online resource for genitourinary research.Development (Cambridge, England) · 2011Article
- Article
- Subfractionation of differentiating human embryonic stem cell populations allows the isolation of a mesodermal population enriched for intermediate mesoderm and putative renal progenitors.Stem cells and development · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The discipline of paediatric nephrology encompasses the congenital nephritic syndromes, renal dysplasias, neonatal renal tumours, early onset cystic disease, tubulopathies and vesicoureteric reflux, all of which arise due to defects in normal kidney development. Indeed, congenital anomalies of the kidney and urinary tract (CAKUT) represent 20-30% of prenatal anomalies, occurring in 1 in 500 births. Developmental biologists have studied the anatomical and morphogenetic processes involved in kidney development for the last five decades. However, with the advent of transgenic mice, the sequencing of the genome, improvements in mutation detection and the advent of functional genomics, our understanding of the molecular basis of kidney development has grown significantly. Here we discuss how the advent of new genetic and genomics approaches has added to our understanding of kidney development and paediatric renal disease, as well as identifying areas in which we are still lacking knowledge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.